D-异抗坏血酸饱和脂肪酸酯的合成  

Synthesis of Saturated Alkanoyl-6O-D-isoascorbates

作　　者：郑大贵[1] 肖竹平[1] 叶红德[1] 

机构地区：[1]上饶师范学院江西省普通高校应用有机化学重点实验室,江西上饶334001

出　　处：《合成化学》2008年第1期99-101,共3页Chinese Journal of Synthetic Chemistry

基　　金：江西省普通高校重点实验室科技计划资助项目(赣教技字2005-301)

摘　　要：用浓H2SO4作为反应介质和催化剂,通过直接酯化法或酯交换法合成了5个D-异抗坏血酸脂肪酸(癸酸,月桂酸,豆蔻酸,棕榈酸和硬脂酸)酯,其结构经1H NMR和IR表征。实验结果表明,就粗产物的产率和纯度而言,直接酯化法均比酯交换法高。Five long-chain saturated alkanoyl-6-O-D-isoascorbates （alkanoyl = decanoyl, lauroyl, myristoyl, palmitoyl and stearoyl） were synthesized by esterification （or transesterification） of D- isoascorbic acid with alkanoic acids using concentrated H2SO4 as a medium and a catalyst at room temperature. The structures were characterized by ^1H NMR and IR. The experimental results showed that both the yield and the purity of the crude products obtained from esterification were higher than those from transesterification.

关 键 词：D-异抗坏血酸 D-异抗坏血酸脂肪酸酯 直接酯化法 酯交换法 

分 类 号：O626.11[理学—有机化学]