新生仔猪蛋白质合成的调控机制  

The regulation mechanisms on protein synthesis in neonatal pigs

作　　者：胡琴[1] 李铁军[1] 康萍[1] 石常有[1] 黄瑞林[1] 印遇龙[1] 

机构地区：[1]中国科学院亚热带农业生态研究所动物生态营养与健康养殖联合实验室

出　　处：《生命科学》2008年第1期131-137,共7页Chinese Bulletin of Life Sciences

基　　金：“973”项目(2004CB117502);国家自然科学基金(30771558,30671517);中科院知识创新方向项目(KSCXZ-SW-323);中国科学院海外杰出学者基金(2005-1-4)

摘　　要：仔猪出生后早期阶段能高效地利用日粮氨基酸进行体蛋白质(尤其是骨骼肌蛋白)合成。这种高效的蛋白质沉积与摄食后血浆胰岛素及营养物质(氨基酸、葡萄糖等)水平升高有密切关系,餐后血浆胰岛素、氨基酸及葡萄糖水平的提高,能显著刺激新生仔猪蛋白质合成。本文着重就摄食引起胰岛素及营养物质信号通路的活化对新生仔猪蛋白质合成的作用效果及其作用机制作一综述。The neonatal period is characterized.by high growth rate and protein accretion rate, especially with the most rapid gain occurring in skeletal muscle, which is in part due to the ability of neonatal pigs to markedly increase protein synthesis in response to feeding. Postprandial could rise in insulin and nutrients such as amino acid and glucose, which modulate the protein synthesis significantly. This paper summarizes the effects and mechanisms of feeding-induced activation of early insulin-signaling pathway and nutrients-signaling pathway leading to the stimulation on protein synthesis of neonatal pigs.

关 键 词：蛋白质合成 新生仔猪 胰岛素 信号通路 营养物质 调控 

分 类 号：S858.28[农业科学—临床兽医学] Q578[农业科学—兽医学]