围产期母婴轮状病毒感染的研究  

GRAVIDAS AND THEIR NEONATES ROTAVIRUS INFECTION

作　　者：赵枫[1] 谢孟坤[1] 姚英民[1] 吴建春[1] 钟梅[1] 余秀良 

机构地区：[1]第一军医大学南方医院,510515

出　　处：《新生儿科杂志》1997年第5期193-194,199,共3页The Journal of Neonatology

基　　金：国家自然科学基金

摘　　要：用反转录聚合酶链反应（RT-PCR）方法，对1993年广州市近郊两所医院住院的200例孕妇及其出生三天内的新生儿轮状病毒（HRV）感染情况进行了研究。结果表明母婴HRV感染率分别为27．00％和25．00％。54例HRV感染孕妇中有18例宫颈分泌物中检出HRV，占被检总数的9％（18／200）。母婴配对分析显示，受HRV感染的孕妇所生新生儿HRV感染率高达62．92％，而未感染孕妇所生新生儿HRV感染率仅10．96％，两者差异非常显著（P＜0．01）。18例宫预分泌物HRV阳性孕妇所生新生儿第一天粪便HRV阳性率为50．00％，而宫预分泌物HRV阴性孕妇所生新生儿第1天粪便无一例检出HRV，提示HRV感染孕妇是新生儿HRV感染的重要传染源，分娩过程通过产道感染是新生儿HRV感染的重要传播途径。Two hundred gravidas and their neonates within postnatal 3 days in obstetrical words intwo hospitals of Guangzhou Cith were innestigated by RT-PCR fro human rotavirus(HRV)infection. HRV was tested in feces and excretion of cervix. Among Zoo gravidas and theirneonates,the HRV infection rates were 27. 00% (54/200) and 25.00% (50/500 ) respectively.In 54 infected gravidas, 18 of them were positive for HRV in excretion of cervix. By maternal-neonatally paired arlalysis,the HRV infection rate of the neonates delivered by the infectedrnother was extremely higher than that of neonates delivered by non-infected mothers. Theresult suggested that the infected mother may be an important reseruoir for HRV infection ofneonate, Labour tract may be a transmission of mother to neonote HRV infection.

关 键 词：人轮状病毒 孕妇感染 新生儿感染 

分 类 号：R714.251[医药卫生—妇产科学] R722.13[医药卫生—临床医学]