羧基酞菁锌与壳聚糖偶联物的制备  

Preparation of chitosan conjugate with zinc(II) carboxyl phthalocyanine

作　　者：邵宇飞[1] 唐凤翔[1] 

机构地区：[1]福州大学化学化工学院,福建福州350002

出　　处：《福州大学学报（自然科学版）》2008年第1期144-147,共4页Journal of Fuzhou University(Natural Science Edition)

基　　金：福建省自然科学基金资助项目(C0310007);福州大学校人才基金资助项目(XRC-0533)

摘　　要：采用邻苯二甲酸酐为保护剂,对壳聚糖的氨基进行保护.氨基保护的壳聚糖与羧基酞菁锌的活性酯反应,再经脱保护基,得到羧基酞菁锌—壳聚糖偶联物.红外光谱初步确定二者通过酯键偶联,紫外可见吸收光谱显示偶联物有羧基酞菁锌的特征吸收峰,且Q带最大吸收峰红移,并据此得出偶联物中羧基酞菁锌与壳聚糖的表观摩尔比为3∶1.The amino groups of chitosan （CTS）were protected by phthalic anhydride in this paper. The CTS with amino groups protected reacted with the active ester of zinc（Ⅱ） carboxyl phthalocyanine. After the deprotection of amino groups, the conjugate was obtained finally. IR spectra analysis showed that the ester bond was formed between zinc（Ⅱ） carboxyl phthalocyanine and CTS through. The conjugate had the UV absorption of carboxyl phthalocyanine, and its λmax= of Q band exited red shift phenomenon from UV- Vis spectra. And zinc（Ⅱ） carboxyl phthalocyanine bound CTS with the apparent molar ratio of 3 ： 1.

关 键 词：壳聚糖 羧基酞菁锌 偶联 

分 类 号：TQ464.1[化学工程—制药化工]