部分脾栓塞治疗难治性原发血小板减少性紫癜  

Partial Splenic Embolization in the Treatment of Refractory Idiopathic Thrombocytopenie Purpura

作　　者：陈虎[1] 周健[1] 杨德琪[1] 

机构地区：[1]杭州市第一医院放射科

出　　处：《实用放射学杂志》1997年第8期475-477,共3页Journal of Practical Radiology

摘　　要：目的：探讨ＰＳＥ治疗难治性原发血小板减少性紫癜的临床应用价值。方法：对６２例经内科治疗无效的ＲＩＴＰ，采用Ｓｅｌｄｉｎｇｅｒ′ｓ法，经股动脉穿刺，脾动脉置管，注射明胶海绵作部分脾栓塞治疗，以期提高患者周围血小板计数，治愈或减轻出血症状。结果：本组６２例ＲＩＴＰ经ＰＳＥ治疗后，获ＣＲ３９例（６２．９％）；ＰＲ１３例（２１．０％）；总有效率８３．９％。１年后复查，复发率２９．０％。结论：ＰＳＥ治疗ＲＩＴＰ与脾切除无显著性差异（Ｐ＞０．０５），可作为脾切除的替代手术。Objective:To study the clincal significance of partial splenic embolization(PSE)in treatment of refractory idiopathic thrombocytopenic(RITP).Methods:62 cases of RITP which had been failed of internal medicine therapy were accepted for PSE in order that their platelet count world be incresed and hemorrhagic symptoms be remitted or cured.According to the Seldinger′s partial splenic embolization was done by infusion of gelfoam into the splenic artery via femoral artery.Results:39 cases were CR(62.9%),13 cases were PR(21.0%),The total effective rate was 83.9%.The recurrent rate was 29.0% after one year.Conclusion:It′s nosignificant difference between the therapy of PSE and splenectomy(p>0.05)in treatment of RITP.PSE can be regareded as a substituted method of surgical splenectomy.

关 键 词：脾栓塞 血小板减少性 紫癜 明胶海绵 

分 类 号：R554.605[医药卫生—血液循环系统疾病]