脑弥漫性轴索损伤96例分析  

Analysis of Clinical Characteristics of 96 Patients with Diffuse Axonal Injury

作　　者：陆林其[1] 崔尧元[2] 盛罗平[1] 周浩[2] 陈仁辉[1] 周仲民 

机构地区：[1]复旦大学附属中山医院青浦分院神经外科,上海201700 [2]复旦大学附属中山医院神经外科,上海200032 [3]江苏省宜兴市第二人民医院神经外科,江苏宜兴300234

出　　处：《中国临床医学》2008年第1期28-30,共3页Chinese Journal of Clinical Medicine

摘　　要：目的:分析脑弥漫性轴索损伤(diffuse axonal injury,DAI)的临床特点与预后。方法:回顾总结96例DAI的临床特点,如受伤原因、影像学变化、诊断入院后GCS、瞳孔、血糖的变化和预后的关系。结果:DAI患者多发生于车祸与坠落滚动伤,96例患者恢复良好30例,中残14例,重残12例,植物状态生存3例,死亡37例。结论:DAI应根据受伤机制、临床特点、CT或MRI影像及早正确诊断,DAI死亡率高。其轴突损伤严重程度,GCS高低,昏迷持续时间,血糖和瞳孔变化有助于DAI病情评估及预后的判断。Objective：To analyze the clinical characteristics and prognosis of cerebral diffuse axonal injury （DAI）. Methods：A retrospective study was done in 96 petitnts with DAI The clinical data including causes, image manifesbortion, GCS, diagnosis, purple and blood gluconse were reviewed. Analyzed the relationship hetween the clinical index and prognosis. Results： The main cause of DAI were vehicle damage and fulirg damage. The outcome were good 30, medium deformity 14, severe deformity 12, vegetal condition 3, death 37. Conclusion：DAI shounld be diagnosed early based on damage mechanism, clinical characteristic and CT or MRI manifestation. The axonal injury desree, GCS, persisting comatire, blood glucouse and purple are related with prognosis.

关 键 词：脑弥漫性轴索损伤 临床特点 预后 

分 类 号：R651.15[医药卫生—外科学]