用于免疫分析的α-萘酚和β-萘酚人工抗原的合成与表征  

Synthesis and characterization of artificial antigen for α-naphthol and β-naphthol

作　　者：高珊珊[1] 庄惠生[1] 周纯[1] 

机构地区：[1]东华大学环境科学与工程学院,上海201620

出　　处：《化学试剂》2008年第2期81-84,共4页Chemical Reagents

基　　金：国家自然科学基金资助项目(20677008)

摘　　要：α-萘酚和β-萘酚经过氯乙酸法改造结构,引入羧基,再经活化酯法与载体蛋白BSA偶联,成功合成了α-萘酚和β-萘酚人工抗原,为其免疫分析方法的建立提供了条件。产物结构经红外、核磁共振和紫外光谱鉴定分析确定。The artificial immune antigen of α-naphthol and β- naphthol have been successfully synthesized by chloroacetic acid method followed by coupling with BSA, which made it possible to establish the immunoassay for α-naphthol and β-naphthol. The structure of the products was determined by IR, IHNMR and UV spectroscopy.

关 键 词：Α-萘酚 Β-萘酚 人工抗原 合成 鉴定 

分 类 号：O529.7[理学—高压高温物理]