金属药物研究新进展  

Progress in investigation of metallodrugs

作　　者：柴晓华[1] 王飞利[1] 黄洁[1] 张君[1] 

机构地区：[1]西北大学化工系,陕西西安710069

出　　处：《化学试剂》2008年第2期99-104,共6页Chemical Reagents

基　　金：陕西省自然科学基金资助项目(2006B02);西北大学科学研究基金(03NW23)

摘　　要：综述了近10年用于诊断和治疗的几种重要金属药物,主要介绍了MRI造影剂、金属酶模拟物、金属抗炎剂、NO调节剂及抗肿瘤药物等,最后对金属药物的发展前景作了展望。This paper reviewed some important diagnostic and therapeutic metallodrugs developed over the last decade, which were mainly associated with the MRI contrast agent, metal enzyme simulacrum, metal anti-inflammatory agent, nitric oxide modulator, anti-tumor complexes, etc. finally, the possible future for development of metallodrugs was reviewed.

关 键 词：金属药物 造影剂 金属酶 抗癌药物 

分 类 号：O614[理学—无机化学] R97[理学—化学]