用抗人IgM(μ链)单克隆抗体早期诊断风疹病毒感染  

Early Diagnosis of Rubella Virus Infection with Monoclonal Antibody against Human IgM (μChain)

作　　者：龚镇奎[1] 黄鹤[1] 骆林[1] 肖红雨[1] 

机构地区：[1]湖北省医学科学院病毒所,武汉430079

出　　处：《中国病毒学》1997年第3期281-283,共3页Virologica Sinica

基　　金：湖北省科委资助

摘　　要：An indirect ELISA by using monoclonal antibody (McAb) against hutnan IgM (μ chain)as the antibody labeled with horseradish peroxidase (second antibody) is used in detecion Rubela virus - specific IgM for early diagnosis of Rubella virus infection. Through the detection and verifition of a large number of sera from normal population, the population closely contacted with Rubella virus and IgM - positive sera samples of Measles virus, cycoegaforirm and Toxplasma Gondii, it is indicated that this method is specific, seusiuive, simple, rapid and no cross - reaction with the positive sera of the pathogens menticned above, It can be used for early diagnosis of Rubella virus infection and epidemiological survey.An indirect ELISA by using monoclonal antibody (McAb) against hutnan IgM (μ chain)as the antibody labeled with horseradish peroxidase (second antibody) is used in detecion Rubela virus - specific IgM for early diagnosis of Rubella virus infection. Through the detection and verifition of a large number of sera from normal population, the population closely contacted with Rubella virus and IgM - positive sera samples of Measles virus, cycoegaforirm and Toxplasma Gondii, it is indicated that this method is specific, seusiuive, simple, rapid and no cross - reaction with the positive sera of the pathogens menticned above, It can be used for early diagnosis of Rubella virus infection and epidemiological survey.

关 键 词：风疹病毒感染 抗人IgM(μ链) 单克隆抗体 诊断 

分 类 号：R511.204[医药卫生—内科学]