2100例妇科成年女性宫颈支原体感染及药敏分析  

作　　者：龙辉 肖淑君 崔艳萍 

机构地区：[1]清远市妇幼保健院,广东清远511515

出　　处：《现代保健（医学创新研究）》2008年第4期13-14,共2页

摘　　要：目的了解本地区女性生殖道临床感染解脲支原体（Uu）和人型支原体（Mh）的分布及抗生素的药敏谱现状，为临床诊疗及合理用药提供依据。方法应用支原体培养、鉴定、药敏一体化试剂盒，对2100例疑为支原体感染患者的宫颈分泌物进行支原体培养、鉴定分型，并测定其对10种常用抗生素的敏感性。结果2100例可疑病例中支原体培养阳性1155例（55％）。其中单纯Uu阳性者940例，占44．8％，单纯Mh感染者67例，占3．2％，Uu与Mh混合感染148例，占7％。药敏结果表明，支原体对10种抗生素敏感率较高的是交沙霉素（95．5％）、克拉霉素（93．6％）、阿奇霉素（91．7％）、而耐药最高为环丙沙星（61．1％），其次为氧氟沙星（59．4％）。结论本地区女性宫颈口临床感染支原体主要为解脲支原体Uu；交沙霉素等新一代大环内酯类抗生素为首选药物，喹诺酮类抗生素耐药率最高。Objective To understand the present situation of drug susceptibility of antibiotics and distribution urine ureaplasma（Uu） and mycoplasma hominis（Mh） infection in local women and to provide proof for clinical treatment. Methods Cervical discharge of 2100 suspected women was cultured for mycoplasma and identified for classification, and tested the susceptibility of 10 common - used antibiotics. Results 1155 patients of 2100 suspected cases were positive for mycoplasma culture （accounting for 55% ） ;among whom 940 patients were positive for Uu（ accounting for 44.8% ） ,67 patients positive for Mh （ accounting for 3.2% ）, 148 patients positive for combination of Uu and Mh （ accounting for 7% ）. Results of drug susceptibility indicated that mycoplasma -susceptible antibiotics were Josamycin （95.5 % ）, Clarivhromycin（93.1% ）, Acithromycin（91.7% ）, and mycoplasma- resistant antibiotics were Ciprofloxacin （61.1% ） , Ofloxacin （59.4%）. Conclusion The predominant mycoplasma of cervical infection for local wonen is Uu ,new generation of macrolides like Josamycin is the drug of first choice while quinolones are the most resistant antibiotics.

关 键 词：成年女性 宫颈分泌物 支原体感染 药敏分析 

分 类 号：R446.1[医药卫生—诊断学]