大蒜膏贴敷神阙穴整复人体心率和血压昼夜节律的研究  

Study on the circadian rhythm regulation of heart rate and blood pressure by pasting garlic cream on acupoint Shenque

作　　者：黄泳[1] 石娜[2] 王升旭[1] 陈静[1] 卓鹰[3] 

机构地区：[1]南方医科大学中医药学院针灸教研室,广东广州510515 [2]临沂市人民医院康复中心,山东临沂276003 [3]兰州军区乌鲁木齐总医院,新疆乌鲁木齐830000

出　　处：《皖南医学院学报》2008年第1期22-25,共4页Journal of Wannan Medical College

基　　金：全军"十五"医药卫生科研基金项目(01Q070);全军"十一五"医药卫生科研基金项目(2006MA086)

摘　　要：目的:观察神阙穴外贴大蒜膏对抗睡眠剥夺所致昼夜节律紊乱的整复作用,初步探讨大蒜膏整复昼夜节律紊乱的机理。方法:将20名健康成年男性随机分为三组:正常对照组(A)、睡眠剥夺组(B)、睡眠剥夺并贴药组(C),对B和C组同时进行48h睡眠剥夺,A组不做任何处理,观察A组及睡眠剥夺后B和C组的血压和心率的昼夜变化。结果:A组心率卯时最低,午时最高,二者之间差异有显著性意义(P<0.01),呈现近似昼夜节律变化,峰值为241.654,大约出现在16:11;B组心率卯时最低,子时最高,二者相比没有显著性意义(P>0.05),近似节律消失;C组的心率在卯时最低,酉时最高,二者之间差异有显著性意义(P<0.01),也呈现近似昼夜节律变化,峰值270.744,出现在18:05左右,与A组相比没有出现明显的漂移。三组的收缩压和舒张压都没有近似节律性(P>0.05)。结论:大蒜膏穴位贴敷可以调整人体紊乱的昼夜节律,在一定程度上促进节律的恢复。Objective ：To observe the regulating function of garlic cream on circadian rhythm disturbance resulted from sleep deprivation（SD） by pasting the cream on acupoint Shenque and initially study its mechanism. Methods ：Twenty healthy young men were randomly allocated to normal group （A）, sleep deprivation group （B） and treatment group （C）. Volunteers in group B and C experienced sleep deprivation within a duration of 48h and group C were treated simultaneously by garlic cream pasted on acupoint Shenque, whereas volunteers in group A were permitted to have a normal sleep order without additional treatment. After 48 hours of sleep deprivation, heart rate and blood pressure in all the volunteers were recorded for examination and comparison. Results： Changes of the heart rate in group A preented with a circadian rhythm with the peak value of 241.654 that marked at 16： 11, and the heart rate arrived at the lowest point at Maoshi （ 05 ： 00 - 07： 00, the time system in China before the introduction of clock） and reached its highest point at Wushi （ 11 ： 00- 13： 00 ）, which showed an obvious difference between the two points （P〈0.01）. The heart rate in group B declined to the lowest point at Maoshi （05：00-07：00） and peaked at Zishi （23： 00-01：00）, with no difference between the two points （P 〉 0.05）, and the heart rate seemed to be in absence of circadian rhythm. The changes of the heart rate in group C demonstrated a circadian rhythm with peak value of 270. 744 that labeled at 18：05, which had no definite difference when compared with group A, and the heart rate came down to the lowest point at Maoshi （05：00 - 07：00） and climbed the highest point at Youshi （17：00 - 19：00）, and the difference was significant between the two points （P〈0.01）. No changes of systolic pressure and the diastolic pressure in the three groups were detected in terms of circadian rhythm （ P 〉 0.05）. Conclusion ： Garlic cream pasting on acupoint Shenque

关 键 词：大蒜膏 穴位贴敷 睡眠剥夺 昼夜节律 

分 类 号：R544.1[医药卫生—心血管疾病] R256.340.5[医药卫生—内科学]