尿毒康合剂的质量标准研究  

The Study of Standard of Niaodukang Mixture Quality

作　　者：雷素云[1] 罗清[1] 吴惠妃[1] 钟希文[1] 梁食[1] 

机构地区：[1]中山市中医院药学部,广东中山528400

出　　处：《中华中医药学刊》2008年第3期593-595,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：中山市科技计划项目基金资助项目(2005A117)

摘　　要：目的:建立尿毒康合剂的质量控制方法。方法:采用薄层色谱法鉴别黄芪、大黄。用高效液相色谱法测定大黄中的大黄酚含量。结果:大黄酚在48～132μg范围内线性关系良好(r=0.9996),平均回收率为97.54%,RSD为3.67%。结论:本方法操作简便,结果可靠,重现性好,可作为尿毒康合剂的质量控制方法。Objective ： Establish a method for the quality control of Niaodukang mixture. Methods ： RadixAstragali, Radix et Rhizoma Rheii, Radix Salviae mitiorrh izae were identified by TLC. Chrysophanol was determined by the method of HPLC. Results ：The quantification method had the linearrange of 48 - 132μg and the linearity relation was fine（ r = 0.99963 ）. The average recovery was 100.89% and its RSD was 3.67%. Conclusion ：The quality standard of the mixture was provided. The methods for identification and quantification were simple, reproducible and realizable. It was the quality control method of the niaodukang mixture.

关 键 词：尿毒康合剂 大黄酚 高效液相法 薄层色谱法 

分 类 号：R285.5[医药卫生—中药学]