城市儿童缺铁与铅中毒关系的探讨  

Analysis of the relationship between iron deficiency and lead poisoning in urban children

作　　者：朱章华[1] 臧玉玲[1] 王锁英[1] 韩晓玲[1] 

机构地区：[1]江苏大学附属医院儿科,江苏镇江212001

出　　处：《中国妇幼保健》2008年第3期347-348,共2页Maternal and Child Health Care of China

摘　　要：目的：了解城市儿童缺铁（ID）与铅中毒的关系。方法：先后间隔（9．3±4．6）个月，分两次测定1275名儿保门诊儿童的血铅浓度、血红蛋白、平均红细胞体积（MCV）和红细胞分布宽度（RDW）。进行缺铁与发生铅中毒的Logisitic回归分析。结果：两次检测均无缺铁组（NID）作为对照组，两次检测均为缺铁组（第1组）预测铅中毒的优势比（OR值）为5．54（95％CL：2．25～13．62）；第1次缺铁，第2次无缺铁组（第2组）OR值为2．73（95％CL：0．90～8．27）；第1次无缺铁而第2次为缺铁组（第3组）OR值为0．81（95％CL：0．10～6．30）。结论：城市儿童缺铁更易导致铅中毒，营养不足的儿童加强铁的供应有利于预防铅中毒。Objective： To determine if iron deficiency （ID） is longitudinally associated with lead poisoning. Methods： Successively spacing （9. 3 ±4. 6） months , blood lead levels, hemoglobin, mean corpuscular volume （ MCV）, red cell and distribution width （RDW） were determined for 1 275 children in twice. Did Logisitic regression analysis for iron deficiency and the occurrence of lead poisoning. Results： Using children who were iron - replete at both twice visits as the reference group, children with ID at both twice visits （ the first group）, the OR for predicting lead poisoning was 5. 54 （95% CL, 2. 25 ～ 13.62） . For children with ID at the first visit and iron - replete at the second visit （the second group）, the OR was 2.73 （95% CL： 0. 90 ～8.27）, and for children iron -replete at the first visit and ID at the second visit （the third group）, the OR was 0. 81 （95% CL： 0. 10～6. 30） . Conclusion： The children with ID in urban are more easily supervene lead poisoning. Iron supplementation can prevent lead poisoning in undernourished children.

关 键 词：缺铁铅 中毒 儿童 

分 类 号：R179[医药卫生—妇幼卫生保健]