持续小剂量速尿联合白蛋白治疗婴儿急性脑水肿的临床观察  

Effect of low-dose and durative application of lasix combined with albumin on rescuing infant cerebral edema

作　　者：蒋迎佳[1] 杨涛[2] 唐远平[2] 黄东平[2] 李容汉[2] 

机构地区：[1]四川省妇幼保健院,610031 [2]广东省妇幼保健院

出　　处：《中国妇幼保健》2008年第4期570-571,共2页Maternal and Child Health Care of China

摘　　要：目的：探讨持续小剂量速尿联合白蛋白对急性脑水肿的疗效。方法：将32例急性脑水肿随机分为持续小剂量速尿（0．1～0．2mg／kg／h，持续15～20h／d）联合白蛋白治疗组（观察组）16例，常规甘露醇（0．5g／kg／次，间隔4～6h）治疗组（对照组）16例。结果：观察组脑水肿完全缓解，明显优于对照组，血清钠明显高过对照组，死亡率显著低于对照组。结论：持续小剂量速尿联合白蛋白能有效减轻脑水肿，降低颅内压。Objective： To determine the effect of low - dose and durative application of lasix combined with albumin in rescuing infant cerebral edema. Methods： 32 patients were divided into two groups. Group A was given lowdose and durative application of lasix （ 0. 1 -0. 2 mg/kg/h, 15 -20 h/d） combined with albumin. Group B was given mannitol （0. 5 g/kg/dose, q4 -6 h） . Results： The cere- bral edema area significantly decreased in Group A compared with that in Group B （P 〈0.01 ） . Conclusion： Application of lowdose and durative of lasix combined with albumin can reverse cerebral edema and intracranial hypertension.

关 键 词：婴儿 脑水肿 白蛋白 速尿 

分 类 号：R725[医药卫生—儿科]