TCT及阴道镜病理学对宫颈病变诊断的临床价值  

The clinical value of thin prep cytology test (TCT),colposcopy and biopsy to the diagnosis of cervical disease

作　　者：刘睦宇 彭春香[1] 陈冬梅[1] 

机构地区：[1]广东省珠海市计划生育服务中心,519015

出　　处：《中国妇幼保健》2008年第5期709-711,共3页Maternal and Child Health Care of China

摘　　要：目的:评价液基细胞学检测技术(TCT)、阴道镜检查及病理学诊断对宫颈病变的临床价值。方法:运用TCT对1926例妇产科门诊和妇检门诊就诊的妇女进行初筛,检出宫颈病变139例,之后进行阴道镜检查及病理组织学检查,以病理组织学为金标准。结果:TCT和阴道镜检查对LSIL的检出率分别为55.17%和93.10%,对HSIL的检出率分别为54.54%、90.90%,对CC的检出率分别为66.67%、100.00%。二者差异有统计学意义(P=0.000),TCT和阴道镜诊断CIN以上的敏感性分别为46.51%和82.25%,特异性为95.91%和93.07%(P>0.05),TCT和阴道镜的符合率分别为44.74%和82.25%(P=0.000)。结论:TCT技术应用于宫颈细胞涂片筛查,能明显提高涂片满意率和宫颈异常细胞检出率,联合阴道镜及病理组织学检查,可提高宫颈病变的检出率和准确性。Objective： To evaluate the clinical value of thin prep cytology test （TCT）, eolposeopy and colostomy and biopsy in the diagnosis of cervical intraepithelial and biopsy in the diagnosis of cervical diseases. Methods： 1 926 outpatients in Department of Gynecology were given thin player cytology examinations. 139 cases of abnormal pellicle further underwent colposcopy and biopsy. Pathohistology was golden standard for the diagnoses of different methods. Results： TCT and colposeopy diagnosed the diretion rate were 55. 17% and 93. 10% （P=0. 00）. HSIL were 54. 50% andg0. 90% （P=0. 000） respectively, CCwere66. 67% and 100% （P=0. 000） respectively. The sensitivity of diagnosis CIN with TCT and colposcopy were 46. 50% and 82. 25% （P=0. 00）, respectively, specificity were 95. 91% and 93. 07% （P 〉 0. 05 ） respectively, total consistent rate were 44. 74% and 82. 25% （P = 0. 000） respectively. Conclusion： TCT can increase the satisfactory rate of smears as well as detection rate of abnormal cervical cells can be combined with colposcopic examination and biopsies for dinical diagnosis. In this way the detection rate and accuracy of cervical diseases can be improved.

关 键 词：液基薄层细胞检查 阴道镜 宫颈病变 

分 类 号：R446[医药卫生—诊断学] R711.74[医药卫生—临床医学]