恶性梗阻性黄疸患者根治性手术后肾功能不全高危因素分析  

Studies on high risk factors of renal insufficiency after radical operation of malignant obstructive jaundice patients

作　　者：李丽[1] 叶志霞[2] 邵雪晴[1] 赵玲[1] 邱海燕[1] 

机构地区：[1]第二军医大学附属东方肝胆外科医院麻醉科监护室,上海市200438 [2]第二军医大学附属东方肝胆外科医院护理部,上海市200438

出　　处：《中华护理杂志》2008年第3期201-203,共3页Chinese Journal of Nursing

基　　金：上海市科学技术委员会科研计划项目基金资助(基金编号054119531)

摘　　要：目的探讨恶性梗阻性黄疸患者根治性手术后肾功能不全的高危因素。方法回顾性研究272例患者的一般资料、实验室检查结果、术中情况及术后并发症发生情况,应用SPSS10.0软件包对上述临床资料进行Logistic回归分析,并对结果采用FisherPs判别分析。结果23例患者术后发生肾功能不全。Logistic回归结果显示,影响该类患者术后发生肾功能不全的高危因素包括:胰十二指肠切除术、术中低血压时间、术中出血量、手术前后尿素氮的变化率和手术前后血肌酐的变化率。通过FisherPs判别分析得到3个判别函数。结论通过判别方程预见患者术后发生肾功能不全的危险性,早期采取干预措施,减少患者肾功能不全发生率。Objective To investigate the high risk factors of the renal insufficiency after surgery of malignant obstructive jaundice patients. Methods Data were collected from 272 patients, which includes clinical data, laboratory results, complications during and after operations. The data were analyzed by SPSS10.0 Logistic regression analysis and Fisher＇s discriminant analysis. Results There were 23 patients with complication of renal insufficiency after operation. There were 5 high risk factors of renal insufficiency included pancreaticoduodenectomy, amount of and serum creatinine before and after operation. Blood loss and hypotension during operation, variation rates of blood urea nitrogen were available according to Fisher＇s discriminant analysis. Conclusion According to Fisher＇s discriminant analysis, we can predict the risk of renal insufficiency after operation and take some measures to decrease the incidence of renal insufficiency.

关 键 词：黄疸 梗阻性 外科手术 肾功能不全 

分 类 号：R473.73[医药卫生—护理学]