应用组织速度和应变率成像技术对比研究急性心肌缺血时左室压力变化对左房功能的影响  被引量:2

The effect of left ventricular pressure changing on left atrium function compared between tissue velocity and strain rate imaging under acute left ventricular ischemia

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作  者:陈晓峰[1] 穆玉明[1] 唐琪[1] 王春梅[1] 关丽娜[1] 吐尔逊娜依.阿迪 

机构地区:[1]新疆医科大学第一附属医院心脏超声诊断科,新疆乌鲁木齐830000

出  处:《中国医学影像技术》2008年第2期180-184,共5页Chinese Journal of Medical Imaging Technology

基  金:新疆维吾尔自治区自然科学基金项目(200421101)

摘  要:目的应用组织速度成像(TVI)和应变率成像(SRI)技术研究左室局部心肌缺血时左室压力变化对左房功能的影响并对比两种技术相关指标在病理状态下的变化趋势。方法11只犬行左冠状动脉前降支结扎,制作左室前壁急性心肌缺血模型,应用TVI和SRI技术分别测量缺血前后心房各壁的收缩期峰值速度(VS)、舒张早期峰值速度(VE)、舒张晚期峰值速度(VA)、收缩期应变率(SSR)、舒张早期应变率(ESR)和舒张晚期应变率(ASR)。同时记录二尖瓣口和肺静脉频谱各指标,并以左心导管记录缺血前后左室压力变化曲线。结果心肌缺血后左房各壁VE、VA、SSR、ESR和ASR与缺血前相比增高(P<0.001),左室舒张末期压力(LVEDP)增高且其缺血前后变化率LVEDP%分别与左房前壁、侧壁和下壁的VA变化率VA%呈正相关(r=0.72,0.73,0.83,P=0.05,0.05,0.002)。结论左房功能在局部心肌缺血时会受到增高的LV-EDP影响,表现为左房壁心肌纤维的运动能力随之增加;SRI技术各指标与TVI各指标变化相比在总体上具有同一趋势,但TVI指标在反映这一变化趋势上可能更加趋于稳定。Objective To evaluate whether left ventricular (LV) pressure changing will affect the left atrium (LA) function during the LV ischemia using tissue velocity imaging (TVI) and strain rate imaging (SRI). Methods Eleven healthy dogs were occluded with left anterior descending coronary artery (LAD) for regional acute ischemia. Peak systolic velocity (VS), early diastolic velocity (VE), late diastolic velocity (VA), systolic peak strain rate (SSR), early diastolic strain rate (ESR) and late diastolic strain rate (ASR) of LA walls and catheter-measured pressure of LV were measured at pre and post ischemia respectively. Results VE, VA, SSR, Esr and Asr values increased after ischemia (P〈0.001). Left ventricular end diastolic pressure (LVEDP) increased after ischemia (P〈0.0001) and its changing rate LVEDP% positively correlated with VA% of anterior, lateral and inferior wall respectively (r=0.72, 0.73, 0.83, P=0.05, 0.05, 0.002). Conclusion LA function will be partially affected by the LVEDP changing raised by regional LV ischemia. Presented as the compensated increased wall deformation after regional acute LV ischemia. Both SRI and TVI can refelect this tendency but TVI maybe more accurate in this process.

关 键 词:组织速度成像 应变率成像 左室压力 左房功能 

分 类 号:R542.2[医药卫生—心血管疾病] R445.1[医药卫生—内科学]

 

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