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作 者:李江涛[1] 穆玉明[1] 唐琪[1] 王春梅[1] 关丽娜[1]
机构地区:[1]新疆医科大学第一附属医院心脏超声诊断科,新疆乌鲁木齐830000
出 处:《中国医学影像技术》2008年第2期189-192,共4页Chinese Journal of Medical Imaging Technology
基 金:新疆维吾尔自治区自然科学基金项目(200421101)
摘 要:目的运用应变率成像技术(SRI)和组织速度成像技术(TVI)对犬左室急性心肌缺血状态下右心功能的变化进行对比研究。方法10只犬,分别于冠状动脉左前降支结扎前、后10min采集心尖四腔切面图像,测量缺血前后右室壁、右房壁及三尖瓣环的收缩期峰值应变率和运动速度(SSR、VS)、舒张早期峰值应变率和运动速度(ESR、VE)、舒张晚期峰值应变率和运动速度(ASR、VA)、右室射血分数(RVEF)和用导管法测肺动脉收缩压(PASP)。结果左室局部急性心肌缺血后,RVEF、右室壁和三尖瓣环的应变率及运动速度指标均降低,PASP、右房壁的SSR、ASR、VS和VA均增加。心肌缺血前:RVEF与右室壁及三尖瓣环的SSR呈正相关,RVEF与右室壁及三尖瓣环的VS相关性均无统计学意义。缺血后:RVEF值与右室壁及三尖瓣环的SSR、VS均呈正相关。PASP与右室壁SSR呈负相关,其与右室壁VS相关性无统计学意义。结论左室前壁急性心肌缺血后,SRI及TVI技术对右心功能的检测均显示右室壁舒缩功能减退,右房壁舒缩功能代偿性增加的相似结果。但在PASP与右室壁SR和TVI相关性研究中两者有一定差别,SRI较TVI能更加准确反映其相关性。Objective To evaluate right ventricular function by strain rate imaging (SRI) and tissue velocity imaging (TVI) in left ventricular myocardial acute ischemia.Methods Ten dogs were subjected to left anterior descending coronary artery occlusion and were collected the imaging in apical four-chamber views at baseline and 10 minutes after the left anterior descending artery (LAD) occlusion respectively. Peak SR and tissue velocity of systole (SSR, VS), early diastole (ESR, VE), and late diastole (ASR, VA) in right ventricular wall, right atrium and tricuspid annulus and right ventricular ejection fraction (RVEF) were measured and pulmonary arterial systolic pressure (PASP) was acquired with catheterization at pre and post ischemia. Results After acute left ventricular ischemic, RVEF, strain rate and tissue velocity in right venticular wall and tricuspid annulus were decreased (P〈0.05), PASP, SSR, ASR and VS, VA in right atrium were increased (P〈0.05). RVEF was positively correlated with SSR in right ventricular wall and tricuspid annulus before ischemia; RVEF was positively correlated with both SSR and VS in right ventricular wall and tricuspid annulus, PASP was negatively correlated with SSR in right ventricular after ischemia. Conclusion SRI and TVI can be used to evaluate the impaired function of right ventricle and compensatorily increased function of right atrium after acute left ventricular ischemia of anterior wall. SRI could be more sensitive to reflect the relationship between PASP and right ventricular wall.
分 类 号:R542.2[医药卫生—心血管疾病] R445.1[医药卫生—内科学]
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