脊痛舒治疗腰椎间盘突出症的实验研究  

THE TREATMENT OF LUMBAR INTERVERTEBRAL DISK PROTRUSION BY “JITONG SHU”: An Experimental Study

作　　者：吴兴杰[1] 张灵[1] 邓庆芝[1] 

机构地区：[1]黑龙江中医药大学第一附属医院

出　　处：《中医正骨》1997年第6期3-5,共3页The Journal of Traditional Chinese Orthopedics and Traumatology

摘　　要：建立家兔化学性神经根炎模型，模拟腰椎间盘突出症，使用中药脊痛舒注射液局部注射治疗。观察了对模兔活动征象，并进行了血液流变学和病理学检查，以及滤纸片重量测定等。结果表明该药能使模兔血液粘滞度降低，减轻炎症反应程度，减轻神经根的变性，抑制异物肉芽肿生长，从而减轻对近旁神经根的损伤和压迫，对模兔患肢的运动、痛觉、触觉的恢复都有促进作用。与对照组比较，均有非常显著差异（Ｐ＜０．００５）。分析认为，脊痛舒治疗腰椎间盘突出症的作用机制，与该药能够改善微循环、减轻炎症反应以及其具着行气、止痛、活血。n order to imitate lumbar intervertebral disk protrusion, rabbit models of chemical radiculoneuritis were made and treated by local injection of “JITONG SHU” (JTS) (a TCD injection for spondylalgia). The observation of active signs, examination of blood reology and pathology, and determination of filter paper weight showed that JTS could reduce blood viscosity, alleviate inflammatory reaction and nerve root degeneration, inhibit foreignbody granuloma growth, and thus decrease injury and compression of nearby nerve root and promote the recovery of activity, pselaphesia and algesia of the affected limbs of the rabbit models. There was a significant difference in JTS group from the control (p<0.005). Through analysis, if was considered that the mechanism of JTS for lumbar intervertebral disk protrusion lies in its function to improve microcirculation, alleviate inflammatory reaction, promote diuresis, qi flow and blood circulation, and stop pains.

关 键 词：腰椎间盘突出 中医药疗法 脊痛舒 注射剂 

分 类 号：R274.915.3[医药卫生—中西医结合]