维持性血液透析患者代谢综合征流行病学调查  

Prevalence of the metabolic syndrome in maintenance hemodialysis patients

作　　者：张文欣[1,2] 龚智峰[1,2] 彭小梅[1,2] 徐碧云[1,2] 唐盛[1,2] 黄文坛[1,2] 

机构地区：[1]广西壮族自治区人民医院泌尿内科 [2]广西血液净化治疗中心,南宁530021

出　　处：《内科》2008年第1期21-24,共4页Internal Medicine

基　　金：广西科学基金项目(桂科基0575039)

摘　　要：目的了解维持性血液透析(MHD)患者代谢综合征(MS)的发病率及特点。方法以2004年中国糖尿病学会提出的MS诊断标准对我院2000年至2006年维持性血液透析患者进行回顾性、横断面调查。结果386例患者原发病构成:糖尿病19.7%、高血压21.0%、慢性肾炎及其它疾病59.3%。MS总的发病率为39.9%;糖尿病、高血压、慢性肾炎及其它疾病MS发病率分别为94.7%,59.3%,14.8%;女性、男性发病率分别为42.3%和38.1%。整个群体MS相关异常组分:高血压97.4%,低高密度脂蛋白47.2%,高甘油三酯40.4%,高血糖29.5%,肥胖16.7%。结论维持性血透患者有较高MS发病率,大样本、前瞻性研究有助于阐明MS在MHD患者中的发病规律及对预后的影响。Objective To investigate the prevalence of metabolic syndrome in maintenance hemodialysis patients with end-stage of kidney disease. Methods Retrospective, cross-sectional study of 386 maintenance dialysis patients from 2000 to 2006 was used . The definition of criteria of metabolic syndrome required at least 3 of the following 4 defined by China Diabetes Society in 2004 ： abdominal obesity, elevated fasting glucose, elevated blood pressure,elevated triglyceride levels or low high-density lipoprotein cholesterol. Results Primary end-stage of kidney disease manifest：diabetes accoounted for 19.7%, hypertension 21.0%, chronic nephritis and other disease 59.3%. The prevalence of total maintenance hemodialysis was 39.9% with 94.7% in diabetes,59.3% in hypertension, 14.8% in chronic nephritis and other disease. The prevalence of females was 42.3% ,and 38.1% of males. The component of hypertension was 97.4% ,high TG was 40.4% ,low HDL was 47.2% ,high fasting glucose was 29.5% ,obesity was 16.7%. Conclusions The metabolic syndrome is highly prevalent in maintenance dialysis patients. Further large scale and prospective research is required in order to clarify the precise role of this syndrome in patients of MHD.

关 键 词：终末期肾病 维持性血液透析 代谢综合征 心血管疾病 发病率 

分 类 号：R589[医药卫生—内分泌]