乳康胶囊TLC鉴别及含量测定  

Study on the Quality Control of Rukang Capsule

作　　者：王建明[1] 王岩松[1] 马晓星[1] 王凯乾[1] 

机构地区：[1]黑龙江中医药大学中医药研究院,黑龙江哈尔滨150040

出　　处：《中国中医药信息杂志》2008年第3期49-51,共3页Chinese Journal of Information on Traditional Chinese Medicine

摘　　要：目的确定乳康胶囊质量标准。方法通过薄层色谱法对处方中浙贝母、玄参、乳香、天冬进行定性鉴别。运用高效液相色谱-蒸发光散射法对黄芪中的黄芪甲苷进行含量测定。结果定性鉴别从样品中能检出相应的斑点。黄芪甲苷含量在1.44～4.32μg之间有良好的线性关系。回收率为100.3%,RSD=0.5%。结论所建立的方法可靠,能准确地进行定性、定量检测,可以用于本制剂的质量控制。Objective To formulate the quality standard of Rukang Capsule. Method The TLC of Zhebeimu, Xuanshen, Ruxiang and Tiandong were done separately. The HPLC-ELSD was used to determine the content of Astragaloside in Mongolian Milkretch Root. Result There were the same spots between the controls and samples and an excellent linear relationship for 1.44-4.32μg to the content determination of Astragaloside. The average recovery can reach 100.3% with 0.5% of RSD. Conclusion This method is reliable and accurate to application, and can be used for the quality control of the preperafion.

关 键 词：乳康胶囊 黄芪甲苷 薄层色谱法 高效液相色谱法 

分 类 号：R284.1[医药卫生—中药学]