二维应变评价肺动脉高压患者右室收缩期应变能力  

Assessment of Right Ventricular Systolic Myocardial Deformation Using Two-dimensional Strain in Patients with Pulmonary Hypertension

作　　者：童春[1] 黎春雷[1] 宋家琳[1] 张洁[1] 段炼[1] 杨霞[1] 邓又斌[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院超声影像科,武汉市430030

出　　处：《中国超声医学杂志》2008年第3期233-236,共4页Chinese Journal of Ultrasound in Medicine

摘　　要：目的应用二维应变软件定量分析肺动脉高压患者右室收缩期应变能力,并探讨不同程度肺动脉高压对右室收缩期峰值应变(Strain,S)及峰值应变率(strain rate,SR)的影响。方法应用二维应变软件测量29例肺动脉高压患者和31例正常人的右室游离壁及室间隔各节段心肌收缩期峰值S、SR,在二维应变的模式下于心尖四腔观勾画右室心内膜面,测量并记录右室游离壁及室间隔基底段、中段及心尖段收缩期峰值S、SR,比较各收缩期峰值S、SR在肺动脉高压组与正常人组间有无差异,并比较轻、中及重度肺动脉高压组间各测值有无差异。结果肺动脉高压患者的右室收缩期峰值S、SR低于正常人。随肺动脉高压程度的加重,右室收缩期峰值S、SR下降程度加重。结论二维应变可以用来评价肺动脉高压患者收缩期应变能力,肺动脉高压患者收缩期应变能力受损,肺动脉高压程度重者,其收缩期应变能力受损程度重。Objective To assess right ventricular myocardium deformation in patients with mild, moderate, and severe pulmonary hypertension using two-dimensional strain. Methods Peak myocardial systolic strain （S）, strain rate （SR） were measured respectively in right ventrieular free wall and basal, mid and apical segment in ventrieular septum in 29 patients with pulmonary hypertension （age range, 13-77 years 13 man, mean age 38.00±15.64） and 31 age-matched controls using two-dimensional strain from the apical 4-chamber view. Results Peak systolic myocardial strain, and strain rate were lower in patients with pulmonary hypertension than those in controls and were the lowest in patients with severe pulmonary hypertension. Conclusions Two-dimensional strain may prove useful for studying RV myocardium deformation which was impaired in patients with pulmonary hypertension. Compared with the controls, S and SR is mostly impaired in patients with severe pulmonary hypertension.

关 键 词：肺动脉高压 二维应变 右心室功能 

分 类 号：R543[医药卫生—心血管疾病] R445.1[医药卫生—内科学]