定量组织速度成像技术评价肥厚型心肌病患者的收缩后收缩  

Assessment of Postsystolic Shortening in Hypertrophic Cardiomyopathy Patients via Quantitative Tissue Velocity Imaging

作　　者：黄猛[1] 张新书[1] 王玲[1] 吴媛媛[1] 

机构地区：[1]安徽医科大学第一附属医院超声科,合肥市230022

出　　处：《中国超声医学杂志》2008年第3期240-244,共5页Chinese Journal of Ultrasound in Medicine

基　　金：安徽省教育厅自然科学基金(No.KJ2007B203)

摘　　要：目的探讨定量组织速度成像技术(QTVI)评价肥厚型心肌病患者在等容舒张期出现的收缩后收缩(PSS)现象及临床意义。方法利用定量组织成像技术检测17例肥厚型心肌病患者和15例正常对照者的心肌,测量收缩期峰值(Vs)、舒张早期峰值(Ve)、舒张晚期峰值(Va)和PSS峰值速度及持续时间,并计算Ve/Va。结果对照组的生理性PSS出现率约22%,多位于室间隔、前壁的基底、心尖段;肥厚型心肌病的病理性PSS出现率约68.9%,PSS峰值速度增大,持续的时间延长。结论肥厚型心肌病的病理性PSS和对照组的生理性PSS有明显差别。利用定量组织速度成像技术(QTVI)有助于理解病理性PSS的机制,并指导临床的诊断和治疗。Objective To assess postsystolic shortening （PSS） and its clinical meanings during isovolumic relaxation phase in regional myocardium in HCM patients and normal persons by quantitative tissue velocity imaging （QTVI） . Methods Left ventricular regional myocardia in 17 HCM patients （HCM group ） and 15 normal persons （control group） were assessed by quantitative tissue velocity imaging. Regional systolic （Vs）, early diastolic （Ve）, end diastolic （Va）, postsystolic shortening velocities （Vpss） and post systolic shortening time （Tpss） were measured at each segment of ventricular basal, middle and apical levels, and Ve/Va ratio was calculated. Results In the control group, the rate of PSS was 22%, especially at basal and apical segment of ventricular septum and anterior wall. In HCM group, the rate of PSS was 68.9%, the peak velocities became higher and the time became longer. Conclusions Physiologic PSS are different from pathologic PSS. QTVI can be used to understand the mechanism of PSS and to guide clinical diagnosis and therapy.

关 键 词：定量组织速度成像技术 肥厚型心肌病 收缩后收缩 

分 类 号：R542.21[医药卫生—心血管疾病]