复方托吡卡胺滴眼液致突发性耳聋  

Sudden deafness due to compound tropicamide eye drops

作　　者：逄雯丽[1] 姜莉莉[1] 张德宪[1] 

机构地区：[1]青岛市海慈医院内分泌科,山东青岛266000

出　　处：《药物不良反应杂志》2008年第1期65-66,共2页Adverse Drug Reactions Journal

摘　　要：1名60岁女性糖尿病患者,行眼底检查前用复方托吡卡胺滴眼液散瞳,随后出现听力明显下降伴耳鸣,检查提示双耳感音神经性耳聋。经高压氧、葛根素治疗后,听力明显恢复。因眼科检查需要,再次用复方托吡卡胺滴眼液,用药后患者又出现听力明显下降,经对症治疗后好转。当患者第4次使用该药后出现耳聋,治疗1月余,听力仍未恢复。A 60-year-old woman with diabetes was instilled with compound tropicamide eye drops for mydriasis before examination of ocular fundus. She developed a markedly decreased auditory acuity with tinnitus. An examination showed a bilateral sensorineural deafness. After treatment with hyperbaric oxygen and puerarin, her hearing recovered obviously. The patient was instilled with the eye drops again for examination of eye, and then her markedly decreased auditory acuity recurred. Deafness occurred after the fourth instillation of tropicamide eye drops. Despite more than 1 montht treatment, her hearing did not recover.

关 键 词：复方托吡卡胺滴眼液 突发性耳聋 

分 类 号：R595.3[医药卫生—内科学]