临床生化检验参考方法的主要作用  

Roles of reference method in clinical biochemistry

作　　者：陈文祥[1] 申子瑜[1] 杨振华[1] 

机构地区：[1]卫生部北京医院卫生部临床检验中心,100730

出　　处：《中华检验医学杂志》2008年第3期245-249,共5页Chinese Journal of Laboratory Medicine

基　　金：国家科技支撑计划资助项目（2007BA105B09）;国家高技术研究发展计划（863计划）资助项目（2006AA020909）

摘　　要：参考方法是临床检验参考系统的主要组成部分。参考方法主要用于评价常规方法和为标准物质定值，从而建立和保证检验结果的溯源性。常规方法的校准偏倚和非特异性及参考物质的互通性是临床检验标准化中的重要问题，标准化工作也需要互通的参考物质。参考方法在鉴定和纠正常规方法主要质量问题及参考物质研制中发挥不可替代的作用。Roles of reference method in clinical biochemistry were introduced. Reference method is an important component of the reference system. Reference methods are primarily used for the establishment and assurance of the traceability of measurement results through calibrating and evaluating routine methods and assigning values to reference materials. Calibration biases and non-specificities of routine methods and the commutability of reference materials are the major issues in the standardization of clinical biochemistry. Standardization also requires availability of commutable reference materials. Reference methods are irreplaceable tools to identify the issues and to characterize reference materials.

关 键 词：临床化学试验 参考标准 校准 

分 类 号：R686[医药卫生—骨科学]