纤支镜灌洗液经变色液体培养基快速培养结核分枝杆菌对涂阴肺结核诊断价值的研究  

Study on the diagnostic value of rapid culture in BALF with change-colour fluid culture meium in patients with sputum negative pulmonary tuberculosis

作　　者：赵伟[1] 

机构地区：[1]安徽省铜陵市第二人民医院,244000

出　　处：《临床肺科杂志》2008年第4期444-444,446,共2页Journal of Clinical Pulmonary Medicine

摘　　要：目的评价纤维支气管镜小量肺泡灌洗液经变色液体培养基快速培养结核分枝杆菌对涂阴肺结核的诊断价值。方法对40例涂阴肺结核患者分别行纤支镜小量肺泡灌洗、刷检或活检,将灌洗液经变色液体培养基快速培养结核分枝杆菌。结果纤支镜肺泡灌洗40例,灌洗液培养出结核分枝杆菌17例,阳性率42.5%,刷检32例,阳性5例,活检8例,阳性3例,刷检+活检阳性率20%,P<0.05有统计学意义。快速培养检出时间平均13.5天。结论纤支镜灌洗液经变色液体培养基快速培养结核支杆菌,可提高涂阴肺结核中结核分枝杆菌的检出率,缩短了细菌培养检出时间。Objective To evaluate the diagnostic value of rapid culture in bronchoalveolar lavage flui （BALF） with change-colour fluid culture medium in patients with sputum negative pulmonary tuberculosis. Methods Brochial lavaging , brushing and lung biopsying were respectively performed for 40 cases with sputum negative pulmonary tuberculosis and the BALF was rapidly cultured for Mycobacterium tuberculosis. Results Among the total of 40 cases, there were 17 （42. 5 % ） having being Mycobacterium tuberculosis. And the 32 cases who underwent bronchial brushing,5 cases were cultured Mycobacterium tuberculosis, while the 8 cases underwent transbronchial lung biopsy, 3 caseswere cultured. The incidence brushing and biopsy were 20% （ P 〈 0. 05 ）, and it was significant for statistics. The means time of rapid culture was 13.5 days. Condusion The diagnosis rate of sputum negative pulmonary tuberculosis was remarkably higher by rapidly cultured for Mycobacterium tuberculosis in BALFwith change-colour fluid medium. It shortened the time of diagnosis of bacterium culture . And it was value to used.

关 键 词：纤支镜肺泡灌洗 变色液体培养 诊断 涂阴肺结核 

分 类 号：R521[医药卫生—内科学]