冠心病患者脂蛋白(a)和纤维蛋白原血浓度与冠状动脉狭窄间的关系  

The Relationship among Serum Lipoprotein(a), Plasma Fibrinogen Levels and Coronary Stenosis in Patients with Coronary Heart Disease

作　　者：汪芳[1] 赵迎 胡锦章[2] 满咏[3] 王华[1] 

机构地区：[1]卫生部北京医院心内科,北京100730 [2]安徽铜陵有色职工总医院心内科 [3]卫生部北京老年医学研究所生物化学室

出　　处：《中国动脉硬化杂志》1997年第3期246-248,共3页Chinese Journal of Arteriosclerosis

摘　　要：为观察血清脂蛋白（a）、血浆纤维蛋白原浓度与冠心病的冠状动脉狭窄程度的关系，选择137例冠状动脉造影水患者，测定血清脂蛋白和血浆纤维蛋白原水平。结果61倒多支冠状动脉病变的冠心病患者的血清脂蛋白（a）水平明显高于31例无冠状动脉病变者．冠心病组中的单支及多支病变组血浆纤维蛋白原水平均明显高于无病变组。而脂蛋白（a）与纤维蛋白原水平仅在多支病变者中有轻度正相关性。To investigate the relationship between serum lipoprotein (a) [LP (a)], plasma fibrinogen (Fg) levels and coronary stenosis documented by angiography in patients with coronary heart disease (CHD). One hundred and thirty-seven cases undergone coronary angiography whose serum LP (a) and plasma fibrinogen levels were determined. Results show that the serum Lp(a) mean levels were higher in 61 cases of CHD with multi-vessels disease (VD) than 31 control with none vessel disease. Plasma Fg levels raised significantly in CHD cases of single and multiple VD groups than None VD group. There was a mild relation between LP (a) and Fg level in multi-VD group (r = 0. 37, P<0. 05, n = 53). This study suggests that LP (a) and Fg blood levels all increase significantly in CHD cases, and there is certain relation between them.

关 键 词：冠心病 脂蛋白(a) 纤维蛋白原 冠状动脉狭窄 

分 类 号：R541.402[医药卫生—心血管疾病] R543.302[医药卫生—内科学]