IVF-ET中卵巢基质血流动力学变化与卵巢反应性的关系  

Relationship between hemodynamic changes of ovarian stromal and ovary response during in vitro fertilization and embryo transfer

作　　者：李柳铭 吴洪波[1] 袁华[1] 李慕军[1] 

机构地区：[1]广西医科大学第一附属医院妇产科广西生殖医学研究中心,南宁市530021

出　　处：《广西医学》2008年第2期153-156,共4页Guangxi Medical Journal

基　　金：广西科学研究与技术开发计划课题(桂科攻0236027);广西医疗卫生科研课题(桂卫Z200558)

摘　　要：目的在体外受精-胚胎移植(IVF-ET)过程中应用阴道彩色多普勒超声成像技术(TV-CDS)监测双侧卵巢基质血流的阻力指数(RI)、搏动指数(PI)、收缩期峰流速(PSV)的变化,探讨其与卵巢反应性的关系。方法选取在本中心行IVF-ET的54例不孕症妇女,使用TV-CDS测量控制性超排卵(COH)周期用药第1天(D1)、用药后第4天(D4)、hCG注射日(DhCG)、取卵日(DOPU)、卵巢基质血流的RI、PI、PSV。根据获卵总数、用药天数等指标将病人分组后,比较卵巢基质血流的RI、PI、PSV在不同组间的差异。结果(1)COH周期中各取样日PI、RI的差异无统计学意义(P>0.05);(2)D1PI、D1RI越高,用药剂量越大,用药天数越长(P<0.05);(3)D1PI、D1RI、D1PSV在卵巢高、中、低反应组病人中差异有统计学意义(P<0.05)。结论D1卵巢基质血流PI、RI与卵巢反应性有密切关系,是有效预测卵巢反应性的指标。Objective To investigate the value of transvaginal color Doppler in forecasting the ovary response. Methods Fifty four infertile women were divided into three groups according to the number of oocyte collected. PI, RI and PSV of ovary stromal blood flow were examined by transvaginal color Doppler ultrasound on the first day of Gn in COH（ D1 ） ,four days after medication （D4） ,the day of HCG injection （DHCG） and DOPU. The ovary stromal blood flow parameters were compared among three groups. Results （ 1 ） There was no significant difference between PI and RI in COH. （2） The higher of D1PI and D1RI,the more days of treatment and the more doses of Gn were used. （3） PI, RI and PSV in D1 were significantly different among low, normal, high response groups. Conclusion PI and RI of D1 are valuable to predict the ovary response.

关 键 词：体外受精-胚胎移植 经阴道彩色多普勒超声 阻力指数 搏动指数 收缩期峰流速 

分 类 号：R713.7[医药卫生—妇产科学]