小肠CT造影对比剂的优选  

Optimization of contrast agents for small intestine computed tomography enteroclysis

作　　者：宋富珍[1] 程英升[1] 朱悦琦[1] 赵培荣[1] 赵俊功[1] 赵炳辉[1] 

机构地区：[1]上海市第六人民医院放射科,上海市200233

出　　处：《世界华人消化杂志》2008年第4期366-371,共6页World Chinese Journal of Digestology

摘　　要：目的:评价何种对比剂在小肠CT造影时能充分充盈扩张肠管、不易形成伪影,在显示小肠肠腔、肠壁方面最佳.方法:8条健康成年毕格犬麻醉后,插管至十二指肠屈氏韧带以下,静脉注射654-2,经导管注入不同的对比剂:纯水、纯牛奶、10 mL/L泛影葡胺后行MSCT扫描,平扫结束后行增强扫描.通过横断面及多平面重建,测量肠腔宽度、肠壁厚度,对各组测量及评价结果进行统计学分析.同时测量平扫、增强后20 s、30 s、40 s、50 s时肠壁的CT值,测量计算肠腔与肠壁对比程度最好时,肠腔与肠壁密度的CT值差值范围.结果:在肠腔宽度的比较上,纯牛奶组与纯水组、泛影葡胺组的差异有统计学意义(F= 28.115,P<0.01),纯水组与泛影葡胺组无明显统计学差异;在肠壁厚度的比较上,纯牛奶组、纯水组、泛影葡胺组的差异均无明显统计学差异.纯水与纯牛奶组肠腔、肠壁显示最好,此时肠壁与肠腔密度的差值为69.25±6.28 HU.结论:纯牛奶是较理想的小肠CT造影对比剂,能够充分充盈扩张肠腔,同时能够较好的显示肠腔、肠壁的情况.AIM： To evaluate which contrast agents can fully distend the intestinal canal and demonstrate the enteric cavity and intestinal wall in computed tomography （CT） enteroclysis. METHODS： After 8 healthy grown-up Beagles were anesthetized, a catheter was inserted to the Treitz ligament of duodenum, 654-2 was injected through the veins, and different contrast agents including pure water and milk and 10 mL/L angiografin were infused through the catheter. After MSCT plain scanning, enhancement scan- ning was performed. Width of the enteric cavity and thickness of the intestinal wall measured through the transverse section and multi-planar reconstruction were statistically analyzed. Plain scanning of intestinal wall was performed. CT values, contrast coefficient of enteric cavity and intestinal wall density, and difference in enteric cavity and intestinal wall density were measured 20 s, 30 s, 40 s, and 50 s after enhancement scanning. RESULTS： All the beagles finished small-intestine CT enteroclysis. The enteric cavity widths were compared between pure milk, pure water and angiografin groups （F = 28.115, P 〈 0.01）. There was no statistical significance in enteric cavity width between the pure water and angiografin groups, as well as in the thickness of intestinal wall between the three groups. The difference in CT value was 69.25 ± 6.28 HU when the contrast coefficient for the enteric cavity and intestinal wall was the best in pure milk and pure water groups. CONCLUSION： Pure milk is an ideal contrast agent for small-intestine CT enteroclysis, which can fully distend the intestinal canal and demonstrafe the enteric cavity and intestinal wall.

关 键 词：对比剂 小肠CT造影 毕格犬 

分 类 号：R816.5[医药卫生—放射医学]