血小板活化标志物与糖尿病肾病的关系  

Relationship between Markers of Activated Platelet and Diabetic Nephropathies

作　　者：徐海前 柴栖晨[2] 

机构地区：[1]杭州市拱墅区红十字会医院内科,杭州310011 [2]浙江医院内分泌科,杭州310013

出　　处：《医学综述》2008年第5期719-720,共2页Medical Recapitulate

摘　　要：糖尿病患者所发生的一系列理化因素改变可导致血小板的活化,而另一方面,活化的血小板在糖尿病肾病的发生、发展中亦起着重要作用。现对血小板活化标志物的种类(主要为血小板颗粒膜糖蛋白和质膜糖蛋白)及其与糖尿病肾病的密切关系进行综述。以期为临床上对糖尿病肾病患者使用抗血小板活化药物提供理论依据。A series of physicochemical factor changes occurred in pations with diabetes can result in activation of platlet. On the other hand, activated platlet also play an important role in the genesis and development of diabetic nephropathies,This article reviews the marker category of platlet activation（ The main are glucoprotein of granule of platelet and glucoprotein of plasmolemma） and its close relationship with diabetic nephropathies in order to provide theory reference for the application of anti-platlet-activation drugs in clinical patients with diabetic nephropathy.

关 键 词：糖尿病肾病 活化血小板 血小板膜糖蛋白类 P-选择素 流式细胞术 

分 类 号：R587.2[医药卫生—内分泌] R331.143[医药卫生—内科学]