妊娠期肝内胆汁淤积症胎儿监护及围产儿预后的关系  

The correlation between prognosis of fetal electrical monitoring and perinatal fetal in intrahepatic cholestasis of pregnancy

作　　者：金丰梅[1] 陈映婷[1] 

机构地区：[1]广东省珠海市妇幼保健院,519000

出　　处：《中国妇幼保健》2008年第8期1087-1089,共3页Maternal and Child Health Care of China

摘　　要：目的:探讨无负荷试验(NST)和脐动脉血流测定对妊娠期肝内胆汁淤积症(ICP)患者围产儿预后的监护价值。方法:联合应用多普勒测定脐动脉血流速度和胎心无负荷试验,对98例ICP患者(ICP组)及同期的98例正常孕妇(对照组)进行比较。结果:①ICP组胎儿宫内窘迫、新生儿窒息、围产儿死亡的发生率明显高于对照组(P<0.05)。②ICP组脐动脉收缩期最大血流速度与舒张末期血流速度比值(S/D)和胎儿无负荷试验异常发生率明显高于对照组,差异有显著性(P<0.01)。③ICP组中NST、脐血流S/D值结果异常的病例,围产儿预后不良的发生率明显高于结果正常组(P<0.005)。结论:对ICP病例应常规进行NST检查和脐动脉血流S/D测定,以早期发现胎儿宫内窘迫并给予及时处理,可有效改善围产儿预后。Objective： To evaluate the monitoring value of nonstress test （NST） and umbilical artery flow velocity for patients with intrahepatic cholestasis in pregnancy （ICP） . Methods： NST and fetal umbilical artery flow velocity were used in 98 patients with ICP and 98 normal pregnant women. Results： （1）The incidence, for fetal distress, asphyxia of newborn and perinatal mortality rate was significantly higher in ICP group than that in control group （ P 〈 0.05 ） . （2）Ratio for blood stream speed, between contraction stage and diastole last stage （ S/D）, and abnormality rate in fetal non - stress test was significantly higher, there were significant difference （ P 〈0. 01 ） . （3） The incidence of poor perinatal outcome in patients with abnomal NST and S/D was significantly higher than that of the control （P 〈 0.05） . Conclusion： NST and umbilical artery flow S/D ratio analysis should be conventional in ICP cases , to early detect fetal distress and to prompt processing, which can effectively improve perinatal outcome.

关 键 词：妊娠期肝内胆汁淤积症 胎心无负荷试验 脐动脉血流速度 围产儿预后 

分 类 号：R714[医药卫生—妇产科学]