以MnO_2为氧化剂制备3-甲基-2-吡啶甲酰胺  

Preparation of 3-methyl-2-formylaminopyridine Using MnO_2 as an Oxidation Mediator

作　　者：王嫣红[1] 陈日耀[1] 郑曦[1] 陈晓[1] 陈震[1] 

机构地区：[1]福建师范大学化学与材料学院,福建福州350007

出　　处：《福建师范大学学报（自然科学版）》2008年第2期54-56,91,共4页Journal of Fujian Normal University：Natural Science Edition

基　　金：福建省教育厅基金资助项目(JB05314)

摘　　要：在70℃下用化学方法制备3-甲基-2-吡啶甲酰胺,收率为86.6%,并以IR对其进行了结构表征.在此基础上,以电化学方法在超声波震荡下,在稀碱溶液中,阳极生成几纳米至几十纳米尺寸的MnO2,可将2-氰基-3-甲基吡啶氧化为3-甲基-2-吡啶甲酰胺,自身被还原为MnOOH.MnOOH旋即在阳极上又被氧化生成MnO2,MnO2/MnOOH电对在阳极区中循环发生,电流效率66.1%.3-methyl-2-formylaminopyridine was prepared using 2-cyano-3-methylpyridine as a raw material via hydrolysis in basic solution by MnO2 oxidant at 70℃. The yield was 86.6%. The product was identified by IR. With the effect of ultrasonic, the electrogenerated MnO2 granules could reach a nano-level in alkaline conditions, which would act as an oxidant in the electrosynthesis of 3-methyl-2-formylaminopyridine. MnOz could be reduced to MnOOH in the solution, while MnOOH would be oxidized to MnOz immediately on the anode. The current efficiency was 66.1%.

关 键 词：3-甲基-2-吡啶甲酰胺 2-氰基-3-甲基吡啶 MNO2 电合成 

分 类 号：O64[理学—物理化学]