化脓灸对免疫性慢性肝损伤小鼠的抗自由基损伤作用  

Huanongjiu's Anti-free Radical Effects on Chronic Immuno-hepatic Injury

作　　者：吴娟[1] 胥志斌 陈丽[3] 

机构地区：[1]江西中医药高等专科学校,江西抚州344000 [2]抚州市第一医院,江西抚州344000 [3]江西中医药高等专科学校附属医院,江西抚州344000

出　　处：《河南中医》2008年第2期26-28,共3页Henan Traditional Chinese Medicine

基　　金：江西省卫生厅资助课题(编号:2006A41)

摘　　要：目的:研究化脓灸对免疫性慢性肝损伤小鼠抗自由基损伤的作用。方法:制备免疫性慢性肝损伤小鼠模型;选择小鼠血清丙二醛(MDA)含量、谷胱甘肽过氧化物酶(GSH-Px)活力、肝匀浆超氧化物歧化酶(SOD)及病理形态学检查为实验指标,探讨化脓灸对免疫性慢性肝损伤小鼠的抗自由基损伤作用。结果:化脓灸组与模型组相比,小鼠血清MDA含量下降,SOD及GSH-Px活力上升,且抗自由基作用优于阳性对照组。结论:化脓灸对免疫性肝损伤小鼠具有抗自由基损伤的作用。Objective： To research Huanongjiu＇s anti-free radical effects on chronic immuno-hepatic injury of mice. Method： The model rats with chronic immuno-hepatic injury are prepared. And the capacity of rat＇s serum MDA, the energy of Glutathione Peroxidase（GSH-Px）, SOD and pathological morphology were selected as the experimental index, to probe Huanongjiu＇s anti： free radicals effects on chronic immuno-hepatic injury. Results： Comparing with model group, capacity of mice serum MDA decreased in Huanongjiu group, while the energy of SOD and GSH-Px increased, and the effect of anti-free radical was better than that of positive control group. Conclusion： Huanongjiu has the anti-free radical effects on chronic immuno-hepatic injury of mice.

关 键 词：化脓灸 免疫性慢性肝损伤 抗自由基损伤作用 小鼠 

分 类 号：R245.8[医药卫生—针灸推拿学]