2-芳香酰氨基-β-D-吡喃葡萄糖的合成及抗菌活性  

Synthesis and antibacterial activities of 2-aromatic acyl -β-D-glucopyranoses

作　　者：欧阳文竹[1,2] 郭振楚[3] 杜昱光 谭成玉 

机构地区：[1]河南黄淮学院化学化工系 [2]湖南科技大学化学化工学院,湖南湘潭411201 [3]湖南科技大学化学化工学院 [4]大连化学物理研究所

出　　处：《化学研究与应用》2008年第3期290-294,共5页Chemical Research and Application

摘　　要：A series of protected and deprotected 2 - deoxy -2 - aromatic acyl -β- D - glucopyranoses are prepared. Six of them are confirmed by IR,1H NMR,13C NMR and elementary analyses. The preliminary antibacterial activities against staphylococcus albus and escherichia coli are studied. The result show that all the deprotected products has a good antibacterial ability to the two bacterias,while the products protected by acetyl show no activity.A series of protected and deprotected 2 - deoxy -2 - aromatic acyl -β-D- glucopyranoses are prepared. Six of them are confirmed by IR, ^1 H NMR, ^13C NMR and elementary analyses. The preliminary antibacterial activities against staphylococcus albus and escherichia coli are studied. The result show that all the deprotected products has a good antibacterial ability to the two bacterias,while the products protected by acetyl show no activity.

关 键 词：2-脱氧-2-芳香酰氨基-β-D-吡喃葡萄糖 大肠杆菌 白色葡萄球菌 

分 类 号：O624[理学—有机化学]