羧甲基壳聚糖-PEG双缩水甘油醚凝胶微球的制备与表征  

Preparation and characteristics of carboxymethyl chitosan-PEG bisglycidyl ether microsphere

作　　者：赵丽瑞[1,2] 孙多先[1] 刘满英[3] 

机构地区：[1]天津大学化工学院 [2]河北医科大学基础医学院,河北石家庄050017 [3]河北医科大学基础医学院

出　　处：《化学研究与应用》2008年第3期329-332,共4页Chemical Research and Application

摘　　要：Carboxymethylchitosan(CMCTS)-Poly(ethylene glycol) bisglycidyl ether(PEGB) microspheres(CMCP) is prepared and characterized . The CMCP microspheres is made by crosslinking CMC with crosslinking agent poly(ethylene glycol) bisglycidyl ether through electrostatic droplet generator. The characteristics of the microsphere are evaluated by Fourier-transformed infrared(FTIR) spectroscopy, X-ray photoelectron spectroscopy,differential scanning calorimetry and scanning electron microscopy. CMCTS crosslink with PEGB through–NH2 group. The title microspheres could be used as adsorbent for blood purification.Carboxymethylchitosan （CMCTS） - Poly （ ethylene glycol ） bisglycidyl ether （ PEGB ） microspheres （CMCP） is prepared and characterized . The CMCP microspheres is made by crosslinking CMC with crosslinking agent poly（ ethylene glycol） bisglycidyl ether through electrostatic droplet generator. The characteristics of the microsphere are evaluated by Fourier - transformed infrared （FTIR） spectroscopy, X- ray photoelectron spectroscopy, differential scanning calorimetry and scanning electron microscopy. CMCTS crosslink with PEGB through - NH2 group. The title mierospheres could be used as adsorbent for blood purification.

关 键 词：羧甲基壳聚糖 聚乙二醇 XPS DSC 

分 类 号：O636.1[理学—高分子化学]