X射线相位衬度成像的研究进展  

Research progress on X-ray phase contrast imaging

作　　者：胡春红[1] 赵涛[1] 李辉[1] 尹红霞[1] 罗述谦[1] 

机构地区：[1]首都医科大学生物医学工程学院,北京100069

出　　处：《国际生物医学工程杂志》2008年第1期36-40,共5页International Journal of Biomedical Engineering

基　　金：国家自然科学基金重点项目（60532090）;北京市自然科学基金重点项目（7031001）

摘　　要：在临床医学和材料科学等领域，基于吸收衬度的X射线成像技术是一种非常重要的诊断工具。然而，对于生物医学软组织、聚合物或纤维材料等，由于它们对X射线的弱吸收，这种传统X射线成像技术的应用受到了限制。相位衬度成像是目前X射线成像领域的最新前沿技术和研究热点之一，它能检测对X射线弱吸收的轻元素物质，空间分辨率可达微米甚至亚微米量级，与传统X射线吸收成像技术相比具有独特的优势，并且在医学、生物学、材料科学等领域上获得了成功。介绍了X射线相位衬度成像的原理、成像特点和应用情况。X-ray radiographic absorption imaging is an invaluable tool in medical diagnostics and materials science. For biological soft tissue samples, polymers or fiber composites, however, the use of conventional X- ray radiography is limited due to their weak absorption. Phase contrast imaging （PCI） is one of up-to-date subjects＇ in the X-ray imaging field. It can inspect weak absorbing low-Z samples and its spacial resolution is on the order of microns or even sub-microns. So PCI has its particular advantages over traditional X-ray absorption imaging tech- nology. The experiments on PCI have been done successfully in medical, biological and material fields. This paper describes the principle of the X-ray phase-contrast imaging, its imaging features and the status of its application.

关 键 词：相位衬度成像 X射线干涉 衍射增强成像 类同轴 微分相位衬度 

分 类 号：R814.4[医药卫生—影像医学与核医学]