添加剂对偏磷酸钙玻璃陶瓷多孔性能的影响  

Effect of addition reagent on the porosity of calcium metaphosphate glass ceramics

作　　者：吴岳恒[1] 汤顺清[2] 章庆春[1] 毛萱[2] 成安衡[1] 肖学钧[1] 

机构地区：[1]广东省人民医院医学研究中心,广东省广州市510100 [2]暨南大学生物医学工程系,广东省广州市510632

出　　处：《中国组织工程研究与临床康复》2008年第6期1063-1066,共4页Journal of Clinical Rehabilitative Tissue Engineering Research

摘　　要：目的:偏磷酸钙(calcium metaphosphate,CMP)玻璃陶瓷的多孔性能与许多因素相关,如钙磷比、添加剂含量和烧制温度等。通过改变添加剂含量制备不同孔隙率的CMP玻璃陶瓷,观察其成孔差异和降解性能。方法:实验于2006-01/2007-06在暨南大学生物医学工程系和测试中心完成。采用二次烧结法制备3种不同配方的CMP玻璃陶瓷,其配方的主要差异在于添加剂(由Al2O3、MgO、CaF2按3∶2∶1摩尔比例组成)的含量不同,分别为5.4%,6.0%,6.7%。用分析天平称质量,计算3种样品的吸水率、显气孔率和体积密度。采用X射线衍射仪进行3种样品的晶相分析,扫描电镜观察3种样品的表面形貌。计算3种样品的失质量百分比评价其降解性能。结果:①随着添加剂含量的增加,吸水率和显气孔率增大,体积密度减少。②3种样品的X射线衍射图谱基本无差异,结合PCPDFWIN数据库,可知3种CMP玻璃陶瓷的主晶相均为β-Ca(PO3)2晶体。扫描电镜结果表明,随着添加剂含量的增加,样品孔洞数目减少,孔洞直径越来越大。③随着添加剂含量的增加,3种样品的失重百分比分别为7.7%,5.9%和3.4%。结论:通过改变添加剂的含量,可改变钙磷比相同的CMP玻璃陶瓷的多孔性能和降解性能。AIM： Some factors are important to the porosity of calcium metaphosphate （CMP） glass ceramics, for example, the Ca/P ratio, the addition reagent content and the sintering temperature. This study was designed to prepare different porosities of CMP glass ceramics through changing the content of addition reagent, and evaluate the porosity difference and degradation properties. METHODS： The experiment was conducted in the Institute of Biomedical Engineering and Testing Center, Jinan University from January 2006 to June 2007. Three kinds of porous CMP glass ceramics were prepared by sintering method, and their major difference was the content of the addition reagent （composed of Al2O3, MgO, CaF2 by 3 ： 2 ： 1 molar ratio）, which was 5.4%, 6.0% and 6.7%, respectively. Analytic balance method was adopted to measure and calculate the water absorption （Wa）, apparent porosity （Pa） and bulk density （Db）. The crystal phases of three kinds of glass ceramics were detected by X-ray diffraction, the surface topography change was viewed by scanning electron microscopy, and the degradability was calculated by evaluating the loss rate. RESULTS： 1.With the addition reagent increased, Wa and Pa were increased, while Db was decreased.2.There was no significant difference in the X-ray diffraction outcomes among three kinds of glass ceramics, and the crystal phase of these three kinds of glass ceramics was β-Ca（PO3） phase analyzed by PCPDFWIN database. Results of scanning electron microscope showed that, the quality of the holes of the CMP glass ceramics was decreased, but the pore diameter was increased with the addition reagent increased.3.When the addition reagent increased, the loss rate of three kinds of CMP glass ceramics was 7.7%, 5.9% and 3.4%, respectively. CONCLUSION： The porosity and degradation properties of CMP glass ceramics with the same Ca/P ratio can be regulated through changing the content of addition reagent in raw materials.

关 键 词：玻璃陶瓷 多孔 偏磷酸钙 添加剂 生物材料 

分 类 号：R318.08[医药卫生—生物医学工程]