动脉粥样硬化防治研究进展  

Advance in the research of prevention and treatment of atherosclerosis

作　　者：陈良光[1] 刘娟[1] 

机构地区：[1]内蒙古医学院附属人民医院,内蒙古呼和浩特010020

出　　处：《疾病监测与控制》2008年第3期177-179,共3页Journal of Diseases Monitor and Control

摘　　要：降低LDL和升高HDL是防治未发和再发心脑血管病的关键。本文讨论LDL对动脉粥样硬化的危害性和HDL的保护作用、目前调节血脂的各种药物和措施、以及治疗所要达到的血脂目标。健康的生活方式，控制饮食，减肥，戒烟，多体力活动是基本措施；药物以综合用他汀加缓释烟酸及MK-0524，有互补和协同作用，既降LDL又升HDL，可减少药量及其副作用，而达到较好的防治效果，是目前的一项首选。To lower LDL and raise HDL are very important in primary and secondary prevention of cardiocerebral vascular diseases. This pap er discusses the harmfulness of LDL and the protection of HDL on arteriosclerosis, recently used various medications and measures On controlling the blood lipids, and the goals of blood lipids that the treatment wants to achieve. Healthy life style, control of diet, lose weight, give up smokin g and exercise are the basic measures. Combination of medications such as statins, slow released niacin and MK-0524, with their complementary a nd synergistic actions, may lower LDL and raise HDL, reduce drug doses and side effects, and achieve better results in prevention and therapy. T his may be the first choice at present.

关 键 词：高密度脂蛋白 低密度脂蛋白 动脉粥样硬化 他汀 

分 类 号：R541[医药卫生—心血管疾病]