4-烷基-4′-氰基联苯的合成新方法  

New Synthetic Method of 4-Alkyl-4′-cyanobiphenyl

作　　者：未本美[1] 张智勇[1] 王龙彪[2] 王刚[1] 

机构地区：[1]武汉工业学院化学与环境工程系 [2]中国人民解放军61699部队

出　　处：《化学世界》2008年第3期169-171,共3页Chemical World

摘　　要：溴代烷与对溴联苯的格氏试剂在FeCl3催化作用下偶联合成4-烷基联苯，然后碘代、氰解合成了三种4-烷基-4′-氰基联苯液晶化合物，总收率58.1％～63．4％，通过IR、^1HNMR、元素分析等对产品进行了表征。该法具有反应条件温和、步骤少、产率高等优点。4-Alkyl-biphenyl was synthesized by the coupling reaction between Grignard reagent of pbromobiphenyl and alkyl bromide with FeC13 as catalyst. Then, liquid crystal intermediate 4-alkyl-4′- cyanobiphenyl was obtained by iodization and cyanidation of 4-alky-biphenyl, and the total yield was 58. 1%～63.4%. The product was confirmed by IR、^1H NMR and elemental analysis. This method had the advantanges of moderate reaction conditions.short steps and high yield.

关 键 词：4-烷基-4′-氰基联苯 合成 液晶 格氏反应 

分 类 号：O625.67[理学—有机化学]