行为危险因素与乙型肝炎病毒感染者不同结局的关联研究  

Association of the activity risk factors with outcomes of hepatitis B virus infection

作　　者：卢亮平[1,2] 王雪屏[3] 孙国常[4] 曾宪嘉[1] 潘利[1] 李辉[1] 

机构地区：[1]中国医学科学院基础医学研究所、中国协和医科大学基础医学院流行病学与卫生统计学系,北京100005 [2]中国医学科学院基础医学研究所、中国疾病预防控制中心传染病预防控制所,传染病预防控制国家重点实验室,北京102206 [3]北京地坛医院检验科,北京100011 [4]北京顺义区医院检验科,北京101300

出　　处：《中国健康教育》2008年第3期173-175,共3页Chinese Journal of Health Education

基　　金：教育部博士点基金(No.2000002340);北京市科学技术委员会科技计划重大项目(No.H020920020590)

摘　　要：目的了解影响乙型肝炎病毒(HBV)感染不同结局的相关因素,为采取有针对性的控制措施提供科学依据。方法采用整群随机抽样的方法,选取慢性HBV患者207人,自限性HBV感染者148人,对可能影响HBV感染结局的影响因素进行问卷调查,采用Logistic回归分析方法。结果经常在外就餐在慢性HBV组和自限性HBV感染组有统计学差异(P=0.0006);每天吸烟量在10支以上者和每月饮酒量在100个饮酒单位者在两组间存在统计学差异(P=0.0017和P=0.0003)。结论不良生活习惯影响HBV感染的结局,应加强HBV感染者的健康教育,改变不良生活方式,有利于减缓HBV感染的慢性化进程。Objective To realize the risk factors which affect the outcomes of HBV infections and provide some scientific evidences for taking the appropriate methods to prevent the HBV carriers to be chronic hepatitis B patients. Methods Two hundred and seven chronic hepatitis B patients and one hundred and forty-eight self-limited HBV infection were selected by cluster sampling and the factors were investigated for some factors which could affect the outcomes of HBV infection by questionnaire and analyzed by logistic regression. Results The frequency of dinner not at home in chronic HB patients was significantly higher than that in self-limited HBV infections subjects （P = 0.0006） ; the frequencies of people who smoke ten branches or drink 100 units were higher than those in self-limited HBV infections subjects （P = 0.0017; P = 0.0003 ）. Conclusion The bad habits of living could affect the outcomes of HBV infection. We should promote the health education to HBV infection subjects to change their bad habits and it is good to slow down the chronic progress of HBV infection.

关 键 词：乙型肝炎 不同结局 影响因素 

分 类 号：R193[医药卫生—卫生事业管理] R512.6[医药卫生—公共卫生与预防医学]