2型糖尿病下肢血管病变发生率及危险因素研究  

The Incidence of Vascular Lesions in Lower Limbs and its Risk Factors in Type 2 Diabetics

作　　者：马玉琢[1] 马占姝[2] 李明辉[2] 

机构地区：[1]赤峰市医院内分泌科,内蒙古赤峰024000 [2]赤峰学院附属医院CT-MRI泌尿外科室,内蒙古赤峰024000

出　　处：《内蒙古医学杂志》2007年第12期1431-1432,共2页Inner Mongolia Medical Journal

摘　　要：目的：了解2型糖尿病患者下肢血管病变（PVD）发病率，分析PVD的相关危险因素。方法：对2005～2007年在赤峰市医院内分泌科住院治疗的446例2型糖尿病患者进行回顾性分析（单因素及logistic回归分析）。结果：65．02％（290／446）患者多普勒超声检查提示有下肢血管病变。年龄、病程、24h尿蛋白（UAE）、血尿酸（UA）、血肌酐（Cr）、收缩压增高比例、周围神经病变（DPN）比例、冠心病（CHD）比例，在有下肢病变者中均显著增高（P〈0．01）。Logistic回归分析结果表明，年龄、总胆固醇（Tch）、DPN是PVD的独立危险因素（OR=1．086，1．351，2．202）。结论：2型糖尿病患者下肢血管病变发生率高，与年龄、血脂、血压、血糖以及糖尿病其他慢性并发症多种因素相关。Objective：To investigate the incidence of peripheral vascular disease（PVD） in type 2 diabetes, and to analyze the risk factors of PVD. Methods： From 2005 -- 2007 , 446 cases of type 2 diabetes in hospital of chifeng city were retrospectively analyzed. Results： 65.02 % of 446 cases showed PVD by Doppler ultrasound examination. The age, course of disease, the levels of urine protein in 24 hours, blood uric acid（BUA）, serum creatinine（Cr）, the increased ratio of systolic pressure, the ratio of PVD and the ratio of coronary heart disease（CHD） was markedly increased in type 2 diabetes with PVD （P〈0.01）. Logistic results showed age, total cholesterol （Tch） and peripheral neuropathy were independent risk factor for PVD（OR = 1. 086, 1. 351,2. 202）. Conclusion ： The incidence of PVD in type 2 diabetes is higher, which is related to age, blood fat, blood pressure, blood sugar and other chronic complications of diabetes.

关 键 词：2型糖尿病 下肢血管病变 多普勒超声检查 

分 类 号：R587.1[医药卫生—内分泌] R543.5[医药卫生—内科学]