皮层下失语患者的CT图象标准化及脑电地形图对比研究  

A study on subcortical aphasia by CT image standardization and BEAM.

作　　者：毛善平[1] 唐尊立[1] 刘谷珩[1] 蒙振中[1] 

机构地区：[1]湖北医科大学附属第一医院神经内科

出　　处：《卒中与神经疾病》1997年第3期133-135,共3页Stroke and Nervous Diseases

摘　　要：选择经颅脑ＣＴ扫描证实为单侧皮层下病变患者６９例，在发病２周，１月及２月分别进行失语症检查。同时，进行ＢＥＡＭ及ＣＴ图象标准化处理。结果显示，皮层下失语患者病灶多在基底节区偏外侧，偏前部及偏上部。病变偏外侧者及丘脑性失语者脑电地形图异常率高，且此类患者多有较重的听理解障碍，而尾状核受损者失语中有明显的构音障碍及音韵障碍。作者讨论了皮层下失语的临床特点，并认为导致失语的机制多与皮层下病变直接或间接影响皮层语言区（血流量减少、代谢低下）有关，但尾状核似可作为言语的皮层下整合中枢，丘脑可作为皮层下语言中枢，在部分患者的失语中起作用。Sixty-nine patients with unilateral subcortical lesions confirmed by CT scans were studied .Aphasia examinations,BEAM and CT image standardization were performed in two weeks,one month and two months after onset.The results showed that most aphasia patients had lesions in the lateral,front and upper part of basal ganglion.BEAM(Brain Electrical Activity Mapping) is largely abnormal in the aphasia patients of lateral type and thalamic aphasia who had serious auditory comprehension disturbance。Prominent dysarthria and dysprosody occured in aphasia patients with lesions in caudate nucleus.We discussed the clinical manifestations of subcorticd aphasia.We suggested that subcortial aphasia is mostly due to the damage of language related zone of hemisphere caused directly or indirectly by subcortical lesions (blood supply insufficiency and low metabolism).Caudate nucleus and thalamus serves as a subcortical center in controlling language and its disturbance cause aphasia in some patients.

关 键 词：皮导下失语 CT 脑电地形图 失语 

分 类 号：R767.64[医药卫生—耳鼻咽喉科]