量子点CdS与纳米TiO2复合物对HL60存活率的影响  

The effect of QDs-CdS and TiO_2 composites on survival ratios of HL60 cells

作　　者：陈丽[1] 刘庆华[2] 熊建文[2] 

机构地区：[1]广东工业大学物理与光电工程学院,广州510006 [2]华南师范大学物理与电信工程学院,广州510006

出　　处：《光电子．激光》2008年第3期423-426,共4页Journal of Optoelectronics·Laser

基　　金：广东省自然科学基金资助项目(7005845)

摘　　要：采用自组装的方法制备了纳米QDs-CdS/TiO2复合物,并将其以及TiO2用于HL60白血病细胞的光动力实验。在可见光区以5种波长光(412 nm、432 nm、462 nm、511 nm、583 nm)及不同的光能流密度辐照后,用CCK-8法测量光密度OD值。实验结果表明TiO2灭活HL60的PDT效率在5种波长光辐照下都比较低,对应于412 nm、432 nm、462 nm、511 nm、583 nm灭活效率分别为:68.3%、66.5%、65.9%、64.7%、64.1%。在同等实验条件下QDs-CdS/TiO2对HL60的灭活效应要明显高于TiO2,在412 nm处QDs-CdS/TiO2对HL60细胞灭活效率最高达86.5%。The QDs-CdS/TiO2 composites were prepared by self-assembly method, and then were used in the PDT experiment of HL60 cells with TiO2. After radiation of five kinds wavelength visible lights（412 nm,432 nm,462 nm,511 nm,583 nm） with different luminous energy density,OD（optical density） values were measured by CCK-8. The experiment results showed that the PDT efficiency of TiO2 on destruction of HL60 cells was low. Corresponding to the five different lights：412 nm,432 nm,462 nm,511 nm,583 nm,the efficiency respectively was：68.3% ,66.5% ,65.9% ,64.7% ,64.1%. The efficiency of QDs-CdS/TiO2 on destruction of HL60 cells was higher than the efficiency of TiO2 under same conditions. The inactivated efficiency of QDs-CdS/TiO2 on HL60 cells reached 86.5% under the radiation of 412 nm light.

关 键 词：量子点 QDs-CdS/TiO2 光动力疗法 红移 

分 类 号：R318.51[医药卫生—生物医学工程]