氢氧化钙-磷酸体系在沉淀法合成羟基磷灰石过程中原料粒度的影响  

EFFECT OF PARTICLE SIZE OF RAW MATERIAL ON HYDROXYAPATITE SYNTHESIS VIA THE PRECIPITATION METHOD BASED ON Ca(OH)_2-H_3PO_4 SYSTEM

作　　者：王艳莉[1] 董寅生[1] 刘斌[1] 郭超[1] 盛晓波[1] 储成林[1] 林萍华[1] 

机构地区：[1]东南大学材料科学与工程学院,南京211189

出　　处：《硅酸盐学报》2008年第3期373-377,共5页Journal of The Chinese Ceramic Society

基　　金：江苏省高新技术研究(BG2001033);日本板梢子公司资助项目

摘　　要：采用化学沉淀法,分别以3种不同颗粒尺寸的氢氧化钙[Ca(OH)2]与磷酸(H3PO4)反应制备羟基磷灰石(hydroxyapatite,HA)粉末,研究了原料粒度对合成HA的影响。测定了合成过程中溶液的pH值和不同反应时间内合成产物的摩尔比n(Ca)/n(P),并表征了所得粉末的组成、颗粒形貌和粒度分布。研究表明:在采用粒度为57～88μm的中等尺寸的原料时,合成过程中,溶液大部分时间处于较高的碱性范围,得到的HA粉末的纯度高、颗粒尺寸分布范围较窄。采用较大尺寸的原料时,溶液的碱性较低,合成的HA粉末中存在磷酸钙β-Ca3(PO4)2(β-TCP)和氧化钙(CaO)且尺寸分布范围较宽。采用较小尺寸原料时,HA粉末存在较严重的团聚现象,团聚体尺寸较大。Ca(OH)2-H3PO4体系用化学沉淀法制备HA粉末时,Ca(OH)2颗粒尺寸是影响合成过程的重要因素之一。Calcium hydroxide （Ca（OH）2） particles with three different sizes were used to react with orthophosphoric acid （H3PO4） in order to investigate the influence of particle sizes of raw materials on hydroxyapatite （HA） powder synthesis by the chemical precipitation method. The pH values of the solution during reaction and the molar ratio n（Ca）/n（P） of the as-synthesized products in different periods were tested and the phase composition, particle morphology and the granularity distribution of the synthesized HA powders were characterized. When Ca（OH）2 particles with medium sizes of 57-88 μm were used, it was shown that the solution was at a high alkaline level throughout most of the synthesis process. The HA powder was pure and had a narrow particle size distribution. The solution was at a lower alkaline level and impurities of β-Ca3（PO4）2（β-TCP） and CaO appeared in the HA powder when coarse Ca（OH）2 was used;furthermore, the particle size distribution became wider. There was serious aggregation when finer Ca（OH）2 was used, and coarser HA powder could be gained. The results show that the Ca（OH）2 particle size is one of the main factors that influence the synthesis of the HA powder by chemical precipitation reaction based on the Ca（OH）2-H3PO4 system.

关 键 词：羟基磷灰石 原料粒度 氢氧化钙 沉淀法 

分 类 号：TQ174.1[化学工程—陶瓷工业]