新生儿侧脑室容积的三维超声定量研究  

Quantitative study on the volume of lateral cerebral ventricle in neonates with three-dimensional ultrasonography

作　　者：吴长君[1] 李玉丹[3] 王萍[2] 张春梅[1] 刘露阳[1] 

机构地区：[1]哈尔滨医科大学附属第一医院超声科,150001 [2]哈尔滨医科大学附属第一医院新生儿科,150001 [3]浙江大学医学院附属邵逸夫医院超声科

出　　处：《中华超声影像学杂志》2008年第3期221-223,共3页Chinese Journal of Ultrasonography

摘　　要：目的应用三维超声检测新生儿侧脑室容积，探讨性别、胎龄、头围、体质量等因素对新生儿侧脑室容积的影响。方法对255例新生儿以前囟为声窗行颅脑超声探测，获取冠状面第三脑室层面所有扫描数据进行三维重建，并计算侧脑室容积。结果①新生儿侧脑室容积与性别无相关性（P=0．809），与出生孕周呈负相关（r=-0．971），与头围呈正相关（r≥0．645），与体质量无相关性（P〉0．05）；②根据头围（X1）、胎龄（X2）与侧脑室容积（Y）的关系得到回归方程Y=2．298—0．011X，-0．04X2，确定系数R^2为0．932；③新生儿左、右侧脑室容积差异无统计学意义（P=0．993）。结论胎龄为新生儿侧脑室容积的主要决定因素，头围为次要决定因素。脑发育不成熟可导致侧脑室增大。三维超声能准确测量新生儿侧脑室容积，有利于无创性评估新生儿脑发育及颅脑疾病的诊断。Objective To study the volume of lateral cerebral ventricle in neonates with threedimensional ultrasonography （3D-US）, and to investigate the influence of sex, body weight （BW）, head circumference（HC） and gestational age（GA） on it. Methods A total of 255 healthy neonates （GA 28-40 weeks） were examined with 3D cranial ultrasound. The ultrasonography was performed with anterior fontanel as the acoustic window,and the data were aquired at the deck of third ventricle on coronal section. The 3D image on the screen was constructed automatically and the volume of lateral cerebral ventricle was calculated. Results ① There was no correlation between the volume of lateral cerebral ventricle and sex （P = 0. 809）,and there was negative correlation between the volume of lateral cerebral ventricle and GA （r = -0. 971）. The correlation between the volume of lateral cerebral ventricle and HC was positive（ r=0. 645）. There was no correlation between the volume of lateral cerebral ventricle and BW（ P 〉0.05）. ② According to the relationships among HC（ X1 ）, GA（ X 2 ） and volume of lateral cerebral ventricle（ Y ）, a linear regression equation Y = 2. 298 - 0.011 X 1 - 0.04 X2 was obtained（the determinate coefficient R^2 was 0. 932）. ③There was no statistical difference between the left and right volume of lateral cerebral ventricle（ P = 0. 993）. Conclusions ①GA was the main determinative factor and HC was the secondary factor of the volume of lateral cerebral ventricle. ②Developmental immaturity of the brain could induce the enlargement of lateral cerebral ventricle. ③3D-US could measure the volume of the lateral cerebral ventricle in neonates accurately,which would be helpful to the evaluation on the cerebral maturity and the diagnosis of cerebral desease in neonates without wound.

关 键 词：超声检查 三维 婴儿 新生 侧脑室 

分 类 号：R686[医药卫生—骨科学]