同位素稀释多接收电感耦合等离子体质谱法测定血铅  

Determination of Lead in Blood by Isotope Dilution Multicollector Inductively Coupled Plasma Mass Spectrometry

作　　者：王琛[1] 赵永刚[1] 王同兴[1] 张继龙[1] 常志远[1] 李力力[1] 朱留超[1] 陈彦[1] 

机构地区：[1]中国原子能科学研究院,放射化学研究所,北京102413

出　　处：《质谱学报》2008年第2期84-87,共4页Journal of Chinese Mass Spectrometry Society

摘　　要：采用同位素稀释多接收电感耦合等离子体质谱(ID-MC-ICP-MS)法测定血铅。运用同位素稀释法测得整个实验的流程空白Pb的浓度平均值为5.6 ng。对SRM955b level 1和SRM955b level 3标准血样进行分析,测得血样浓度分别为40.2、207.8μg.L-1,测定值落在血样参考值范围之内,证明该方法有效、可靠。利用建立的血铅分析方法,参加了络合型血铅标准物质的定值,得到3种血铅标准样中铅的浓度分别为(102.7±5.5)、(181.7±4.0)、(304.1±3.9)μg.L-1。A method for determination of trace Pb in blood was established by isotope dilution multicollector inductively coupled plasma mass spectrometry （MC-ICP-MS）. The average Pb analytical blank obtained in this laboratory is 5.6 ng. A Nist standard reference materials of （SRM） 955b level 1 and （SRM） 955b level 3 were used to evaluate the accuracy of Pb concentration in blood ;Fhe measured values are 40.2 and 207.8μg · L^-1 respecetively, in good agreement with their certified value. The established method was used for determination the Pb concentration of three blood samples, the uncertainty of measurement results were also analyzed and evaluated . The Pb concentration of three blood samples are （102.7 ±5.5）, （181.7±4.0） and （304.1±3.9） μg. L^-1.

关 键 词：血液 铅浓度 同位素稀释多接收电感耦合等离子体质谱 

分 类 号：O657.63[理学—分析化学]