短期运动对大鼠心肌组织超氧化物歧化酶活性的影响  

Influence of short-term exercises of rats on activity of superoxide dismutase of myocardial tissue

作　　者：侯云英[1] 范秀珍[2] 马志勇[3] 

机构地区：[1]苏州大学医学院,215007 [2]山东大学护理学院,250012 [3]教育部和卫生部心血管重构与功能研究重点实验室,250012

出　　处：《护理研究（上旬版）》2008年第3期590-591,共2页Chinese Nursing Researsh

摘　　要：[目的]研究短期中等强度运动对大鼠心肌组织超氧化物歧化酶(SOD)活性的影响,探讨运动对心脏的保护作用的机制。[方法]将16只Wistar大鼠随机分为运动组和对照组,对运动组大鼠进行游泳训练,对照组正常饲养。训练结束后,取大鼠左心室心肌样品测定SOD活性。[结果]运动组心肌组织锰-SOD活性显著高于对照组(P<0.01),两组总SOD和铜锌-SOD活性差异无统计学意义(P>0.05)。[结论]短期中等强度运动通过升高心肌组织锰-SOD活性发挥保护心脏作用。Objective： To study on the influence of short - term moderate intensity exercises on the activity of superoxide dismutase in myocardium of rats, to probe into mechanism of myocardial tissue protection by exercises. Method： A total of 16 Wistar rats were randomly divided into exercise group and control group. Rats in exercise group had swum for 3 days. Rats of control group had been given normal breeding. After the training, myocardial samples of left ventricle of all rats were taken and SOD activity were deter- mined. Results： The activity of Mn - SOD of exercise group rats was significandy higher than that of control group （P〈0.01）. However, activities of total SOD and Cu - Zn - SOD between the two groups rats were not statistically significant（P 〈 0.05）. Conclusion： Short - term moderate intensity of exercises in rats could enhance Mn - SOD activity to protect heart from injury.

关 键 词：运动 心肌保护 超氧化物歧化酶 

分 类 号：R473.5[医药卫生—护理学]