免疫疗法在系统性红斑狼疮中的应用  

Application of Immunotherapy in Systemic Lupus Erythematosus

作　　者：谢君[1] 林有坤[1] 

机构地区：[1]广西医科大学第一附属医院,南宁530021

出　　处：《医学综述》2008年第6期925-927,共3页Medical Recapitulate

摘　　要：系统性红斑狼疮是一种临床表现复杂的慢性系统性自身免疫性疾病,至今病因不明。一般认为是遗传、环境和性激素等多种因素相互作用造成的机体免疫功能紊乱。应用糖皮质激素和免疫抑制剂可改善系统性红斑狼疮患者的预后,但仍有相当一部分患者对传统治疗方法无效。近年来的研究显示,新的免疫疗法治疗系统性红斑狼疮具有广阔的应用前景。Systemic lupus erythematosus（SLE） is a chronic systemic autoimmune disease with complexed clinical symptoms,the real reason for SLE is still unclear up to now,and many scholars suggested that varied factors should be involved in its disorder of immune function,such as heredity,environment,sex hormone and so on.Glucocorticoid and immunosuppressive agents can improve the prognosis of the patients with SLE greatly,although few patients show no improvement in clinical efficacy with traditional immunosuppressive agents.The recent studies showed that some new strategies for immunotherapy will have brightly foreground for treatment of SLE.

关 键 词：系统性红斑狼疮 树突状细胞 免疫疗法 

分 类 号：R593.241[医药卫生—内科学]