干扰素α-1b联合穿琥宁治疗流行性腮腺炎疗效观察  被引量:2

Clinical effect of interferon α-1b combined with Chuanhuning in the treatment of epidemic parotitis

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作  者:努尔陶[1] 哈尔山 黄萃[1] 鲍冰[1] 

机构地区:[1]武警新疆总队医院感染科,新疆乌鲁木齐830091 [2]武警新疆总队阿克苏支队卫生队,新疆阿克苏843000

出  处:《武警医学院学报》2008年第1期23-24,共2页Acta Academiae Medicinae CPAPF

摘  要:【目的】评价干扰素α-1b合穿琥宁对流行性腮腺炎治疗效果。【方法】随机将90例流行性腮腺炎患者分为治疗组及对照组。治疗组给予穿琥宁10~15 mg/kg加入5%葡萄糖100ml中静滴,1次/d,α-1b干扰素100万IU,肌注,1次/d,连用3 d。对照组:在常规治疗基础上,板兰根冲剂,每次5~10 g,3次/d,给予利巴韦林10~15 mg/kg,静滴,1次/d,疗程5 d。【结果】治疗组在控制发热、消肿、并发症等指标显著优于对照组,在统计学上两组间具有显著性差异。【结论】干扰素α-1b合穿琥宁治疗流行性腮腺炎具有疗效肯定、见效快、副作用少等优点,宜临床推广使用。[Objective] To study the clinical effect of interferon α-1b combined with chuanhuning in the treatment of epidemic parotitis. [Methods] A total of 90 patients with epidemic parotitis were randomly allocated into two groups. 45 patients in treatment group were given interferon α-1b 100MU, ira, qd × 3 d, and 10 - 15 mg/kg Chuanhuning in 5% 100 ml glucose injection liquid, once a day. And the control group were given libavirin 10 - 15 mg/ (kg. d)^-1 of injection and with Banlangen 5 - 10 g, 3 times a day. The treatment period for both groups was 5 day. [Results] By comparison, the clinical effect of the treatment group was significantly better than the control (P 〈 0.01). [Conclusions] The clinical effect of interferon α-1b combined with Chuanhuning in treating epidemic parotitis is satisfactory.

关 键 词:干扰素Α-1B 穿琥宁 流行性腮腺炎 

分 类 号:R512.1[医药卫生—内科学]

 

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