Antibacterial Mechanism of Copper-bearing Antibacterial Stainless Steel against E.Coli  

作　　者：Li NAN Weichao YANG Yongqian LIU Hui XU Ying LI Manqi LU Ke YANG 

机构地区：[1]Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, China [2]Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang 110016, China [3]Graduate School of Chinese Academy of Sciences, Beijing 100049, China

出　　处：《Journal of Materials Science & Technology》2008年第2期197-201,共5页材料科学技术（英文版）

基　　金：supported by the National Natural Science Foundation of China(Grant No.50671101).

摘　　要：A preliminary study was made on the antibacterial mechanism of copper-bearing antibacterial stainless steels against E.coli through experiments of microbiology such as EDTA （ethylenediaminetetraacetic acid） complexing, DNA smearing and AFM （atomic force microscope） observation. It was measured that the antibacterial stainless steels showed excellent antibacterial functions with antibacterial rate to E.coli over 99.99%. The antibacterial rate was weak if the bacteria solution was complexed by EDTA, indicating that the copper ions play a dominant role in the antibacterial effect of the antibacterial stainless steels. The electrophoresis experiment did not show the phenomenon of DNA smearing for E.coli after contacting antibacterial stainless steels, which meant that DNA of E.coli was not obviously damaged. It was observed by AFM that the morphology of E.coli changed a lot after contacting antibacterial stainless steels, such as cell walls being seriously changed and lots of contents in the cells being leaked.A preliminary study was made on the antibacterial mechanism of copper-bearing antibacterial stainless steels against E.coli through experiments of microbiology such as EDTA （ethylenediaminetetraacetic acid） complexing, DNA smearing and AFM （atomic force microscope） observation. It was measured that the antibacterial stainless steels showed excellent antibacterial functions with antibacterial rate to E.coli over 99.99%. The antibacterial rate was weak if the bacteria solution was complexed by EDTA, indicating that the copper ions play a dominant role in the antibacterial effect of the antibacterial stainless steels. The electrophoresis experiment did not show the phenomenon of DNA smearing for E.coli after contacting antibacterial stainless steels, which meant that DNA of E.coli was not obviously damaged. It was observed by AFM that the morphology of E.coli changed a lot after contacting antibacterial stainless steels, such as cell walls being seriously changed and lots of contents in the cells being leaked.

关 键 词：COPPER Stainless steel E.COLI Antibacterial mechanism 

分 类 号：TB3[一般工业技术—材料科学与工程]